Journal ArticleDOI
Comparative performance analysis of time–frequency distributions for spectroscopic optical coherence tomography
TLDR
In this article, various joint time-frequency distributions (TFDs) can optimize the trade-off between time resolution and frequency resolution for spectroscopic optical coherence tomography (SOCT) signals.Abstract:
The analysis of spectroscopic optical coherence tomography (SOCT) signals suffers the trade-off between time resolution and frequency resolution. Various joint time–frequency distributions (TFDs) can optimize this trade-off. Synthesized signals were generated and experimentally acquired data were obtained to compare and validate several different TFDs under different SOCT imaging schemes. Specific criteria were designed to quantify the TFD performance. We found that different SOCT imaging schemes require different optimal TFDs. Cohen’s class TFDs generate the most compact time–frequency (TF) analysis, while linear TFDs offer the most reliable TF analysis. In both cases, if some prior information is known, model-based TF analysis can improve the performance.read more
Citations
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Journal ArticleDOI
Optical coherence tomography in dermatology: technical and clinical aspects
TL;DR: An increasing number of papers brought evidence of the utility and the precision of OCT technology, in its different technical variants, in diagnosing and monitoring skin disorders, including malignancies and inflammatory conditions, respectively.
Journal ArticleDOI
Molecular imaging true-colour spectroscopic optical coherence tomography
TL;DR: Molecular imaging true-colour spectroscopic optical coherence tomography (METRiCS OCT) has significant implications for many biomedical applications including ophthalmology, early cancer detection, and understanding fundamental disease mechanisms such as hypoxia and angiogenesis.
Journal ArticleDOI
Optical probes and techniques for molecular contrast enhancement in coherence imaging
TL;DR: In this article, the authors reviewed the use of non-fluorescent and non-bioluminescent molecular imaging probes for coherent optical molecular imaging and their applications in the field of molecular imaging.
Journal ArticleDOI
Computational methods for analysis of human breast tumor tissue in optical coherence tomography images.
Adam M. Zysk,Stephen A. Boppart +1 more
TL;DR: Methods for the assessment of human breast tissue based on spatial and Fourier-domain analysis based on preliminary OCT data are presented, aimed at the development of automated diagnostic tools that will aid in the translation of this technology into the clinical environment.
References
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Journal ArticleDOI
Optical coherence tomography
David Huang,Eric A. Swanson,Charles P. Lin,Joel S. Schuman,William G. Stinson,Warren Chang,Michael R. Hee,Thomas J. Flotte,Kenton W. Gregory,Carmen A. Puliafito,James G. Fujimoto +10 more
TL;DR: OCT as discussed by the authors uses low-coherence interferometry to produce a two-dimensional image of optical scattering from internal tissue microstructures in a way analogous to ultrasonic pulse-echo imaging.
Journal ArticleDOI
The wavelet transform, time-frequency localization and signal analysis
TL;DR: Two different procedures for effecting a frequency analysis of a time-dependent signal locally in time are studied and the notion of time-frequency localization is made precise, within this framework, by two localization theorems.
Book ChapterDOI
Optical Coherence Tomography
Eric A. Swanson,J. Izatt,M. Bee,David Huang,Charles P. Lin,Carmen A. Puliafito,Carmen A. Puliafito,James G. Fujimoto +7 more
TL;DR: Optical coherence tomography (OCT) has developed rapidly since its first realisation in medicine and is currently an emerging technology in the diagnosis of skin disease as mentioned in this paper, where OCT is an interferometric technique that detects reflected and backscattered light from tissue.
Journal ArticleDOI
Time-frequency distributions-a review
TL;DR: A review and tutorial of the fundamental ideas and methods of joint time-frequency distributions is presented with emphasis on the diversity of concepts and motivations that have gone into the formation of the field.
Journal ArticleDOI
Optical biopsy and imaging using optical coherence tomography.
James G. Fujimoto,Mark E. Brezinski,Guillermo J. Tearney,Stephen A. Boppart,Brett E. Bouma,Michael R. Hee,James F. Southern,Eric A. Swanson +7 more
TL;DR: Preliminary studies indicate the feasibility of developing OCT for a wide range of clinical and research diagnostic imaging applications, and the ability to non-excisionally evaluate tissue morphology using a catheter or an endoscope could have a significant impact on the diagnosis and management of a widerange of diseases.