Journal ArticleDOI
Comparison of in vivo dissolution processes in hydroxyapatite and silicon-substituted hydroxyapatite bioceramics
Reads0
Chats0
TLDR
High-resolution transmission electron microscopy observations confirmed that defects, in particular those involving grain boundaries, were the starting point of dissolution in vivo and may help to explain the mechanism by which silicate ions increase the in vivo bioactivity of pure HA.About:
This article is published in Biomaterials.The article was published on 2003-11-01. It has received 391 citations till now. The article focuses on the topics: Bioceramic.read more
Citations
More filters
Book ChapterDOI
Cellular response to hydroxyapatite and Bioglass® in tissue engineering and regenerative medicine
TL;DR: In this paper, the biological responses of various human cells to surface reactive Bioglass®, hydroxyapatite (HA) and their composites for their potential applications in tissue engineering and regenerative medicine were discussed.
Journal ArticleDOI
Bifunctional Bio-Surface Decorated Bone-Grafting Titanium Material with Cancellous Bone-Like Biomimetic Structure for Enhanced Bone Tissue Regeneration
TL;DR: In vitro study demonstrated that this porous Ti scaffold with functional bio-surface could distinctly facilitate cell early adhesion and spreading, and activate the expression of α2β1 integrin receptor on the cell membrane through promoting the formation of focal adhesions in bone marrow stromal cells, thus mediating greater osteogenic cell differentiation.
Journal ArticleDOI
Tailoring of Multilayer Core-Shell Structure for the Controllable Release of Biologically Active Silicon and Strontium Ions
TL;DR: In this article, a layer-by-layer (LbL) assembly of biologically active strontium ions in the core-shell Silica@OCP system for an efficient controlled-release is reported.
Journal ArticleDOI
Halloysite nanoclay reinforced hydroxyapatite porous scaffold for hard tissue regeneration.
Umakant Yadav,Vivek Verma +1 more
TL;DR: In this paper , the authors used halloysite nanoclay (HNC) and sericin protein for better mechanical and osteogenic properties of HAP and showed that the incorporation of HNC in HAP enhanced the cytocompatibility as well as alkaline phosphatase (ALP) activity in comparison to pure HAP.
Book ChapterDOI
Bioinspired ceramics for bone tissue applications
TL;DR: In order to develop bone tissue engineering (BTE) scaffolds, scientists need to mimic the hierarchical design of natural bioceramics along with the appropriate material selection as discussed by the authors .
References
More filters
Book
Theory of Dislocations
John Price Hirth,Jens Lothe +1 more
TL;DR: Dislocations in Isotropic Continua: Effects of Crystal Structure on Dislocations and Dislocation-Point-Defect Interactions at Finite temperatures.
Journal ArticleDOI
Bioactive ceramics: the effect of surface reactivity on bone formation and bone cell function
Paul Ducheyne,Qing-Qing Qiu +1 more
TL;DR: This review describes some of the current concepts regarding the surface reactivity of bone bioactive materials and its effect on attachment, proliferation, differentiation and mineralization of bone cells.
Journal ArticleDOI
Silicon: A Possible Factor in Bone Calcification
TL;DR: Silicon, a relatively unknown trace element in nutritional research, has been uniquely localized in active calcification sites in young bone and is suggested to be associated with calcium in an early stage of calcification.
Journal ArticleDOI
The effect of calcium phosphate ceramic composition and structure on in vitro behavior. II. Precipitation.
TL;DR: The dissolution behavior of the CPCs studied was found to vary over a wide range, and the dissolution rate of the monophase CPCs increased in the order of stoichiometric hydroxyapatite, calcium deficient hydroxyicarbonate, oxyhydroxyapatites, beta-tricalcium phosphate, alpha-tricals calcium phosphate, and tetracalcium phosphate.
Journal ArticleDOI
Chemical characterization of silicon-substituted hydroxyapatite.
TL;DR: Chemical analysis confirmed the proposed substitution of the silicon (or silicate) ion for the phosphorus (or phosphate) ion in hydroxyapatite and demonstrated that phase-pure silicon-substituted hydroxyAPatite may be prepared using a simple precipitation technique.