Journal ArticleDOI
Comparison of in vivo dissolution processes in hydroxyapatite and silicon-substituted hydroxyapatite bioceramics
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TLDR
High-resolution transmission electron microscopy observations confirmed that defects, in particular those involving grain boundaries, were the starting point of dissolution in vivo and may help to explain the mechanism by which silicate ions increase the in vivo bioactivity of pure HA.About:
This article is published in Biomaterials.The article was published on 2003-11-01. It has received 391 citations till now. The article focuses on the topics: Bioceramic.read more
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Structural characterization of silicon-substituted hydroxyapatite synthesized by a hydrothermal method
TL;DR: In this article, a silicon-substituted hydroxyapatite (Si-HA) was prepared successfully by hydrothermal method and the crystalline phase, microstructure, chemical composition, morphology and thermal stability of Si-HA were characterized by X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), transmission electron microscopy (TEM) and differential scanning calorimetry (DSC).
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Ultrastructural comparison of dissolution and apatite precipitation on hydroxyapatite and silicon-substituted hydroxyapatite in vitro and in vivo.
Alexandra E. Porter,Cláudia Botelho,Maria A. Lopes,José D. Santos,Serena M. Best,William Bonfield +5 more
TL;DR: It is suggested that proteins in the in vivo milieu modify the processes of dissolution from the implant, which predominates at the crystallite surfaces in SBF, whereas grain boundary dissolution predominates in vivo.
Journal ArticleDOI
Silicon: the evolution of its use in biomaterials.
TL;DR: This review discusses the current data obtained from original research in biochemistry and biomaterials science supporting the role of silicon in bone, comparing both the biological function of the element and analysing the evolution of silicon-containing biommaterials.
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Bioceramics to regulate stem cells and their microenvironment for tissue regeneration
TL;DR: These findings open up a new direction to explore the possibility of designing new biomaterials for tissue engineering and regenerative medicine based on the specific biological function of the chemical and topographical characteristics of the bioceramics.
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Softening bioactive glass for bone regeneration: sol–gel hybrid materials
TL;DR: In this article, the authors focus on the shift in emphasis from hard, brittle matter to durable, tough materials for bone scaffolds, specifically the development of a particular type of nanocomposite: inorganic/organic hybrids synthesised through the sol-gel process.
References
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Book
Theory of Dislocations
John Price Hirth,Jens Lothe +1 more
TL;DR: Dislocations in Isotropic Continua: Effects of Crystal Structure on Dislocations and Dislocation-Point-Defect Interactions at Finite temperatures.
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Bioactive ceramics: the effect of surface reactivity on bone formation and bone cell function
Paul Ducheyne,Qing-Qing Qiu +1 more
TL;DR: This review describes some of the current concepts regarding the surface reactivity of bone bioactive materials and its effect on attachment, proliferation, differentiation and mineralization of bone cells.
Journal ArticleDOI
Silicon: A Possible Factor in Bone Calcification
TL;DR: Silicon, a relatively unknown trace element in nutritional research, has been uniquely localized in active calcification sites in young bone and is suggested to be associated with calcium in an early stage of calcification.
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The effect of calcium phosphate ceramic composition and structure on in vitro behavior. II. Precipitation.
TL;DR: The dissolution behavior of the CPCs studied was found to vary over a wide range, and the dissolution rate of the monophase CPCs increased in the order of stoichiometric hydroxyapatite, calcium deficient hydroxyicarbonate, oxyhydroxyapatites, beta-tricalcium phosphate, alpha-tricals calcium phosphate, and tetracalcium phosphate.
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Chemical characterization of silicon-substituted hydroxyapatite.
TL;DR: Chemical analysis confirmed the proposed substitution of the silicon (or silicate) ion for the phosphorus (or phosphate) ion in hydroxyapatite and demonstrated that phase-pure silicon-substituted hydroxyAPatite may be prepared using a simple precipitation technique.