Journal ArticleDOI
Comparison of magnetic properties of MRI contrast media solutions at different magnetic field strengths.
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TLDR
Awareness of the field strength and solvent associated with relaxivity data is crucial for the comparison and evaluation of relaxivity values and should be replaced by relaxivities measured at 1.5 T and at 3 T in plasma at physiological temperature.Abstract:
Rationale and Objectives:To characterize and compare commercially available contrast media (CM) for magnetic resonance imaging (MRI) in terms of their relaxivity at magnetic field strengths ranging from 0.47 T to 4.7 T at physiological temperatures in water and in plasma. Relaxivities also were quanread more
Citations
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Recent advances in iron oxide nanocrystal technology for medical imaging
TL;DR: Stem cell migration and immune cell trafficking, as well as targeted iron oxide nanoparticles for molecular imaging studies, are at the stage of proof of concept, mainly in animal models.
Journal ArticleDOI
Strategies for increasing the sensitivity of gadolinium based MRI contrast agents.
TL;DR: This tutorial review describes the molecular factors that contribute to relaxivity and illustrates with recent examples how these can be optimized.
Journal ArticleDOI
Quantum Dots and Their Multimodal Applications: A Review
TL;DR: In this paper, the decoupling of quantum effects on excitation and emission is described, along with the use of quantum dots as sensitizers in phosphors, and the multimodal applications of quantum dot, including in electroluminescence device, solar cell and biological imaging.
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Lanthanide Nanoparticles: From Design toward Bioimaging and Therapy
Hailiang Dong,Shuo-Ren Du,Xiao-Yu Zheng,Guang-Ming Lyu,Ling-Dong Sun,Lin-Dong Li,Pei-Zhi Zhang,Chao Zhang,Chun-Hua Yan +8 more
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Magnetic Nanoparticles: Surface Effects and Properties Related to Biomedicine Applications
TL;DR: The magnetic properties of nanoparticles which are directly related to their applications in biomedicine are discussed, mainly on surface effects and ferrite nanoparticles, and on one diagnostic application of magnetic nanoparticles as magnetic resonance imaging contrast agents.
References
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Journal ArticleDOI
Gadolinium(III) Chelates as MRI Contrast Agents: Structure, Dynamics, and Applications
TL;DR: A. Relaxivity 2331 E. Outerand Second-Sphere relaxivity 2334 F. Methods of Improving Relaxivity 2336 V. Macromolecular Conjugates 2336.
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Paramagnetic metal complexes as water proton relaxation agents for NMR imaging: theory and design
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Characteristics of gadolinium-DTPA complex: a potential NMR contrast agent.
TL;DR: The combination of strong proton relaxation, in-vivo stability, rapid urinary excretion, and high tolerance favors the further development and the potential clinical application of gadolinium-DTPA as a contrast enhancer in magnetic resonance imaging.
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Proton Relaxation Times in Paramagnetic Solutions. Effects of Electron Spin Relaxation
N. Bloembergen,L. O. Morgan +1 more
TL;DR: In this article, it was shown that the distortion of the hydrated complex by collisions with other water molecules is responsible for the decrease in T2 in Mn++ (and other) solutions in very high magnetic fields.
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Proton Relaxation Times in Paramagnetic Solutions
TL;DR: In this paper, an exchange interaction between the electron spin and proton spin in adjacent water molecules in paramagnetic solutions was proposed, and an explanation was given why T1/T2 for protons is much larger than unity in solutions of these particular ions in high magnetic fields, whereas T1 is about equal to T2 in other solutions or in low fields.