Journal ArticleDOI
Competitive binding of bilirubin, sulfobromophthalein, indocyanine green and other organic anions to human and bovine serum albumin.
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TLDR
A number of clinically or physiologically important organic anions, including sulfobromophthalein, indocyanine green, iodipamide, vasoflavine, flavaspidic acid, phenol red, rose bengal and bromcresol green, were tested for their effectiveness in displacing bilirubin from albumin, and the relative affinities of these substances for bilirUBin binding sites on albumin were determined.About:
This article is published in Biochimica et Biophysica Acta.The article was published on 1974-09-13. It has received 66 citations till now. The article focuses on the topics: Bovine serum albumin & Serum albumin.read more
Citations
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Predicting plasma protein binding of drugs: a new approach.
TL;DR: A generic model for the prediction of drug association constants to HSA is reported, which uses a pharmacophoric similarity concept and partial least square analysis (PLS) to construct a quantitative structure-activity relationship.
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Lighting up tumors with receptor-specific optical molecular probes.
TL;DR: This review focuses on the development of receptor-specific molecular probes for optical imaging of tumors by reviewing bioconjugates of probes that absorb and fluoresce in the near infrared wavelengths between 750 and 900 nm.
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Characterization of site I on human serum albumin: concept about the structure of a drug binding site
TL;DR: A model for binding site I is elaborated in which novel nomenclatures, region Ia, Ib, and Ic are proposed for the acenocoumarol, DNSA and n-butyl p-ABE binding regions, respectively.
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Methyl parathion interaction with human and bovine serum albumin
TL;DR: Results suggest that the primary binding site for methyl parathion on albumin is close to tryptophan residues 214 of human serum albumin and 212 of bovine serum albumIn, and suggest that this pesticide is potentially toxic for both vertebrates and invertebrates.
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Journal Article
Protein Measurement with the Folin Phenol Reagent
TL;DR: Procedures are described for measuring protein in solution or after precipitation with acids or other agents, and for the determination of as little as 0.2 gamma of protein.
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Indocyanine green: observations on its physical properties, plasma decay, and hepatic extraction*
TL;DR: Investigations were carried out to determine whether indocyanine green has properties that may render it suitable for assessing liver function and hepatic blood flow in man.
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Two hepatic cytoplasmic protein fractions, Y and Z, and their possible role in the hepatic uptake of bilirubin, sulfobromophthalein, and other anions
TL;DR: Two hepatic cytoplasmic protein fractions, designated Y and Z, which bind sulfobromophthalein (BSP), bilirubin, and other organic anions, have been separated by G75 Sephadex gel filtration and appear to be important in the transfer of Organic anions from plasma into the liver.
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Ligandin: a Hepatic Protein which Binds Steroids, Bilirubin, Carcinogens and a Number of Exogenous Organic Anions
TL;DR: Three protein preparations from the rat liver 100,000g supernatant fraction have been independently purified to homogeneity, and they are basic azodye carcinogen-binding protein (β-ABP), corticosteroid Binder I3,4 and Y protein5.
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Studies in kernicterus. i. the protein binding of bilirubin
TL;DR: The yellow staining of basal ganglia in some jaundiced newborn infants has been recognized for many years and the observation that kernicterus occurred more frequently in premature infants given sulfisoxazole than in control infants despite lower plasma bilirubin concentrations is noted.