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Journal ArticleDOI

Computer calculation of equilibrium constants of species present in mixtures of metal ions and complexing agents.

Sayce Ig
- 01 Dec 1968 - 
- Vol. 15, Iss: 12, pp 1397-1411
TLDR
The program, which employs the non-linear least-squares method, may be used to calculate equilibrium constants for hydrolysed metal ions, protonated ligands, and simple, Protonated, Hydrolysed, polynuclear, and mixed complexes.
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This article is published in Talanta.The article was published on 1968-12-01. It has received 297 citations till now. The article focuses on the topics: Equilibrium constant & Metal ions in aqueous solution.

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A new generation of Ca2+ indicators with greatly improved fluorescence properties.

TL;DR: A new family of highly fluorescent indicators has been synthesized for biochemical studies of the physiological role of cytosolic free Ca2+ using an 8-coordinate tetracarboxylate chelating site with stilbene chromophores that offer up to 30-fold brighter fluorescence.
Journal ArticleDOI

Cytosolic Ca2+ homeostasis in Ehrlich and Yoshida carcinomas. A new, membrane-permeant chelator of heavy metals reveals that these ascites tumor cell lines have normal cytosolic free Ca2+.

TL;DR: The intracellularly trappable fluorescent Ca2+ indicator quin-2 was used to measure free cytosolic Ca2+, [Ca2+]i, in the two highly dedifferentiated tumor cell lines, Ehrlich and Yoshida ascites carcinomas, and it was found that endogenous heavy metals are responsible for partially quenching quin2 fluorescence trapped inside the cells.
Journal ArticleDOI

Miniquad-A general computer programme for the computation of formation constants from potentiometric data.

TL;DR: A new computer programme for the computation of formation constants of complex species in solution is presented, which can be applied to all kinds of potentiometric titration data, including multi-reactant and multi-electrode systems.
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