Journal ArticleDOI
Constant time inverse-detection gradient accordion rescaled heteronuclear multiple bond correlation spectroscopy: CIGAR-HMBC
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TLDR
In this article, a further refinement of the IMPEACH-MBC long-range heteronuclear shift correlation experiment is described, which allows user-determined scaling of F1 modulation.Abstract:
A further refinement of the recently reported IMPEACH-MBC long-range heteronuclear shift correlation experiment is described. The new experiment, CIGAR-HMBC (constant time inverse-detected gradient accordion rescaled long-range heteronuclear multiple bond correlation), modifies the constant time variable delay of the IMPEACH-MBC experiment to allow user-determined scaling of F1 modulation. The refinement offered in the CIGAR-HMBC experiment allows the investigator to reintroduce whatever degree of F1 modulation is desired to authenticate weak long-range responses. Results obtained with the CIGAR-HMBC experiment using a range of values for Jscale are compared with results obtained with identically optimized ACCORD-HMBC and IMPEACH-MBC experiments. Copyright © 2000 John Wiley & Sons, Ltd.read more
Citations
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Journal ArticleDOI
Choosing the Best Pulse Sequences, Acquisition Parameters, Postacquisition Processing Strategies, and Probes for Natural Product Structure Elucidation by NMR Spectroscopy
TL;DR: It is shown that using shorter relaxation delays in combination with forward linear prediction allows one to get better resolved spectra in less time.
Journal ArticleDOI
Survey of NMR experiments for the determination of nJ(C,H) heteronuclear coupling constants in small molecules
TL;DR: A survey of heteronuclear correlation experiments for the measurement of coupling constants is presented in this article, where the authors evaluate several recent experiments for measuring nJ(C,H) (n = 2, 3) couplings in one comprehensive review.
Journal ArticleDOI
Using NMR to identify and characterize natural products
TL;DR: This review will focus on mainly methodology improvements, particularly in pulse sequences, acquisition and processing methods which are particularly relevant to natural product research, with lesser discussion of hardware improvements.
Journal ArticleDOI
Measurement of J(H,H) and long-range J(X,H) coupling constants in small molecules. Broadband XLOC and J-HMBC
Axel Meissner,Ole W. Sørensen +1 more
TL;DR: In this article, a low-pass J filter was employed to eliminate one-bond J(C,H) responses for the measurement of heteronuclear and homonuclear coupling constants.
References
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Journal ArticleDOI
Proton and carbon-13 assignments from sensitivity-enhanced detection of heteronuclear multiple-bond connectivity by 2D multiple quantum NMR
Ad Bax,Michael F. Summers +1 more
Journal ArticleDOI
Gradient-enhanced proton-detected heteronuclear multiple-quantum coherence spectroscopy
Ralph E. Hurd,Boban K John +1 more
Journal ArticleDOI
Direct determination of rate constants of slow dynamic processes by two-dimensional \"accordion\" spectroscopy in nuclear magnetic resonance
TL;DR: In this article, a novel class of NMR expts, based on the systematic variation of 3 time variables, permits both the identification of exchange networks and the direct measurement of the corresponding rate consts.
Journal ArticleDOI
Constant time HMBC (CT-HMBC), a new HMBC technique useful for improving separation of cross peaks
Kazuo Furihata,Haruo Seto +1 more
TL;DR: New NMR pulse sequences CT-HMBC-1 and CT-HBC-2 which incorporate constant time evolution period are more useful than the conventional HMBC technique for improving separation of cross peaks.
Journal ArticleDOI
Excitation-Sculptured Indirect-Detection Experiment (EXSIDE) for Long-Range CH Coupling-Constant Measurement
TL;DR: In this paper, a new pulse sequence (excitation-sculptured indirect detection experiment, EXSIDE) was proposed for measuring long-range heteronuclear coupling constants, which is achieved by a variation of the double pulse-field-gradient spin-echo technique.
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