Constituents from Polygonum cuspidatum.
TLDR
Two lignan sulfates, a stilbene derivative and a phenol sulfate, together with 10 known compounds, were isolated from an aqueous extract of the root of Polygonum cuspidatum showing no inhibition of lipid peroxidation and no cytotoxic and DNA cleavage activities.Abstract:Â
Two lignan sulfates, a stilbene derivative and a phenol sulfate, together with 10 known compounds, were isolated from an aqueous extract of the root of Polygonum cuspidatum. The new compounds were elucidated based on chemical evidence and spectroscopic techniques including two-dimensional NMR methods. They exhibited no inhibition of lipid peroxidation and no cytotoxic and DNA cleavage activities.read more
Citations
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Journal ArticleDOI
Botany, phytochemistry, pharmacology, and potential application of Polygonum cuspidatum Sieb.et Zucc.: A review
TL;DR: The traditional applications as well as advances in botany, phytochemistry, pharmacodynamics, pharmacokinetics and toxicology of Polygonum cuspidatum are reviewed, and the tendency and perspective for future investigation of this plant are discussed.
Journal ArticleDOI
Antibacterial properties of Polygonum cuspidatum roots and their major bioactive constituents
TL;DR: This study suggests that the roots of P. cuspidatum and its antibacterial components may have potential for use as natural preservatives.
Journal ArticleDOI
Naturally Occurring Anthraquinones: Chemistry and Therapeutic Potential in Autoimmune Diabetes
TL;DR: The chemical structure and biological properties of the naturally occurring anthraquinones and their derivatives are outlined with an emphasis on recent findings about their immune regulation, including a new strategy for the use of the anthraquones in autoimmune diabetes.
Book ChapterDOI
Stilbenoids: Chemistry and bioactivities
TL;DR: Stilbenoids are formed by a particular branch of the flavonoid biosynthetic pathway and are of special interest to natural product researchers for their roles in plant resistance to fungal pathogens and their biological effects as discussed by the authors.
Journal ArticleDOI
Analysis of Rhizoma Polygoni Cuspidati by HPLC and HPLC-ESI/MS
Tao Yi,Hao Zhang,Zongwei Cai +2 more
TL;DR: An HPLC method with photodiode array detection (PAD) and ESI/MS detection was developed for the qualitative and quantitative analysis of the major chemical constituents of the dried rhizome of Polygonum cuspidatum Sieb.
References
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Journal ArticleDOI
Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction
TL;DR: Using this method, the liped peroxide level in the liver of rats suffering from carbon tetrachloride intoxication was investigated and was in good agreement with previously reported data obtained by measuring diene content.
Journal ArticleDOI
Cancer Chemopreventive Activity of Resveratrol, a Natural Product Derived from Grapes
Mei-Shiang Jang,Lining Cai,George Udeani,Karla Slowing,Cathy F. Thomas,Chris Beecher,Harry H. S. Fong,Norman R. Farnsworth,A. Douglas Kinghorn,Rajendra G. Mehta,Richard C. Moon,John M. Pezzuto +11 more
TL;DR: It is suggested that resveratrol, a common constituent of the human diet, merits investigation as a potential cancer chemopreventive agent in humans.
Journal ArticleDOI
Plant proanthocyanidins. Part I. Introduction; the isolation, structure, and distribution in nature of plant procyanidins
TL;DR: In this paper, the isolation and determination of structure of some plant procyanidins in their free phenolic forms are described, and the distribution of procyclanidin in the tissues of twentynine plant species has been examined and the biogenetic implications of this study are briefly discussed.
Journal ArticleDOI
Effects of stilbenes on arachidonate metabolism in leukocytes.
TL;DR: The effects of various stilbenes (i.e., 3,4,5-trihydroxystilbene, 3, 4,5,trihydroxylstilbinene 3-O-d -glucoside and 2,3,4',5-tetrahydroxystielbene 2-O-, d-glucose) isolated from the roots of Polygonum species on rat peritoneal polymorphonuclear leukocyte lipoxygenase and cycloencogenase activities were studied in this paper
Journal ArticleDOI
Effects of Stilbene Components of the Roots of Polygonum cuspidatum SIEB. et ZUCC. on Lipid Metabolism
TL;DR: It was found that intraperitoneal or oral administration of resveratrol or piceid reduced triglyceride synthesis from 14C-palmitate in the liver of mice and these stilbene components did not affect hormone-induced lipolysis in fat cells from rat eqididymal adipose tissue.