Journal ArticleDOI
Constituents of the yew trees
V. S. Parmar,Amitabh Jha,Kirpal S. Bisht,Poonam Taneja,S. K. Singh,Ashok Kumar,Poonam,Rajni Jain,Carl Erik Olsen +8 more
TLDR
In this article, taxonomically classified under the genus Taxus, a number of physiologically active compounds of different classes have been extracted from yew trees, including lignans, flavonoids, steroids and sugar derivatives.About:
This article is published in Phytochemistry.The article was published on 1999-04-01. It has received 131 citations till now. The article focuses on the topics: Taxus canadensis & Taxus.read more
Citations
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The biochemistry and medical significance of the flavonoids.
TL;DR: Flavonoids are plant pigments that are synthesised from phenylalanine, generally display marvelous colors known from flower petals, mostly emit brilliant fluorescence when they are excited by UV light, and are ubiquitous to green plant cells.
Journal ArticleDOI
The taxane diterpenoids
TL;DR: The structures of over 350 taxane diterpenoids are classified and presented with information on their plant source, yield, melting point, and optical activity.
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Natural taxanes: developments since 1828.
TL;DR: Natural Taxanes: Developments Since 1828 by Yu-Fang Wang, Qing-Wen Shi,* Mei Dong, Hiromasa Kiyota,* Yu-Cheng Gu, and Bin Cong is based on research conducted at the School of Pharmaceutical Sciences, Hebei Medical University.
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Taxanes in cancer treatment: Activity, chemoresistance and its overcoming
TL;DR: Taxanes have been widely used as microtubule-targeting antitumor agents and have shown impact on key molecular mechanisms including disruption of mitotic spindle, mitosis slippage and inhibition of angiogenesis.
References
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Journal ArticleDOI
The useful plants of India.
TL;DR: The useful plants of India the authors, the useful plants in India, The useful plants from India, useful plants for agriculture, and the useful trees of India, the authors...
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New taxanes from Taxus brevifolia, 2.
TL;DR: The isolation of two taxanes from Taxus brevifolia Nutt is described, together with the isolate of two acetylated taxol derivatives from an acetylation fraction from the same plant.
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Isolation of 9-Dihydro-13-acetylbaccatin III from Taxus canadensis
Geewananda P. Gunawardana,Usha Premachandran,Neal S. Burres,David N. Whittern,Rodger F. Henry,Stephen G. Spanton,James B. McAlpine +6 more
TL;DR: The investigation of Taxus canadensis (Canada yew) needles as a renewable source of taxol and its congeners led to the isolation of a novel taxane derivative, 9-dihydro-13-acetylbaccatin III, which was characterized by spectral analyses and confirmed by single crystal X-ray diffraction studies.
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Taxanes from Taxus baccata
TL;DR: A detailed NMR analysis of the diesters of yew needles allowed an unambiguous assignment of all 1 H and 13 C NMR resonances of these and related taxane derivatives.