Journal ArticleDOI
Convenient preparation of 2‐benzoxazolinones with 1,1‐carbonyldiimidazole
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In this article, a convenient and general preparation of 2-benzoxazolinones from 2-aminophenols with 1,1-carbonyldiimidazole is described.About:
This article is published in Journal of Heterocyclic Chemistry.The article was published on 1982-11-01. It has received 38 citations till now. The article focuses on the topics: Carbonyldiimidazole.read more
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A Small-Molecule Inhibitor of Mps1 Blocks the Spindle-Checkpoint Response to a Lack of Tension on Mitotic Chromosomes
Russell Dorer,Sheng Zhong,John A. Tallarico,Wing Hung Wong,Timothy J. Mitchison,Andrew W. Murray +5 more
TL;DR: The results demonstrate that Mps1 can be exploited as a target and that inhibiting the tension-sensitive branch of the spindle checkpoint may be a way of selectively killing cancer cells that display chromosomal instability.
Journal ArticleDOI
Fate of benzoxazinone allelochemicals in soil after incorporation of wheat and rye sprouts.
Stine Krogh,Susanne Johanne Miriam Mensz,Susan Nielsen,Anne G. Mortensen,Carsten Christophersen,Inge S. Fomsgaard +5 more
TL;DR: This study is the first of its kind that shows the dynamic pattern of biologically active benzoxazinone derivates in soil after incorporation of wheat and rye sprouts.
Journal ArticleDOI
Synthesis of novel 1,2,3-triazole based benzoxazolinones: their TNF-α based molecular docking with in-vivo anti-inflammatory, antinociceptive activities and ulcerogenic risk evaluation.
Saqlain Haider,M. Sarwar Alam,Hinna Hamid,Syed Shafi,Amit Nargotra,Priya Mahajan,Syed Nazreen,Arunasree M. Kalle,Chetna Kharbanda,Yakub Ali,Aftab Alam,Amulya K. Panda +11 more
TL;DR: The molecular docking studies revealed that 3i exhibits strong inhibitory effect due to the extra stability of the complex because of an extra π-π bond, and the histopathology report showed that none of the compounds caused gastric ulceration.
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Occurrence of diboa in wildHordeum species and its relation to aphid resistance
TL;DR: The secondary metabolise DIBOA was found in seedlings of wild Hordeum species, but not of cultivated barley, and correlated negatively with performance of the aphid Rhopalosiphum padi on seedlings.
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Anti-nociceptive and anti-inflammatory activity of some (2-benzoxazolone-3-yl and 2-benzothiazolone-3-yl)acetic acid derivatives.
TL;DR: Among these compounds, 5c, 5d and 5m have exhibited good anti-inflammatory activity, with 5f, and to a lesser extent, the other molecules displaying some toxic potential.
References
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6-methoxybenzoxazolinone: a plant derivative that stimulates reproduction in Microtus montanus.
TL;DR: A plant-derived cyclic carbamate, 6methoxybenzoxazolinone, that stimulates reproductive activity in Microtus montanus has been isolated as discussed by the authors.
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Role of 6-Methoxybenzoxazolinone in Inbred Resistance of Host Plant (Maize) to First-Brood Larvae of European Corn Borer
Jerome A. Klun,T. A. Brindley +1 more
TL;DR: Evidence indicates that 6MBOA is of little consequence in the phenomenon of resistance, however, precursors of 6M BOA may play an active role.
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Naturally occuring modifiers of auxin-receptor interaction in corn: Identification as benzoxazolinones.
Michael A. Venis,P. J. Watson +1 more
TL;DR: The activity of these compounds and the parent analogue in inhibiting auxin binding is correlated with their ability to inhibit auxin-induced growth.