Journal ArticleDOI
Conversion of c14-testosterone to c14-estrogenic steroids by endocrine tissues
Billy Baggett,Lewis L. Engel,Luzmaria Balderas,Gertrude Lanman,Kenneth Savard,Ralph I. Dorfman +5 more
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The ability of stallion testis, human term placenta and a human feminizing adrenal cortical carcinoma to convert C14-testosterone to C 14-labeled estrogenic steroids has been demonstrated and the relationship between this conversion and the biosynthesis of estrogens by these tissues has been discussed.Abstract:
The ability of stallion testis, human term placenta and a human feminizing adrenal cortical carcinoma to convert C14-testosterone to C14-labeled estrogenic steroids has been demonstrated. The relationship between this conversion and the biosynthesis of estrogens by these tissues has been discussed.read more
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Journal ArticleDOI
Estrogen in the adult male reproductive tract: A review
TL;DR: It is concluded that estrogen or its α-receptor is an absolute necessity for fertility in the male and is responsible for maintaining a differentiated epithelial morphology.
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Sources of oestrogen in the testis and reproductive tract of the male.
TL;DR: A lot of work is now focused on this specific area in order to clarify the role of oestrogens in the reproductive tract of the male as well as to elucidate the regulation of aromatase gene expression.
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Estrogen formation in the brain
TL;DR: The reaction seems to be influenced by the hormonal state of the animal, occurs in all species thus far tested, and may represent one mechanism for androgen action in the central nervous system.
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Human testicular aromatase: immunocytochemical and biochemical studies
TL;DR: Activity and immunostain intensity of aromatase did not correlate with increasing age, and the highest levels were measured in four of six testes of men ages 18-20 yr, three of whom also had the strongest Immunostain for aromatasing, providing a semiquantitative estimate of the immunoreaction.
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Estrogens in males: what have we learned in the last 10 years?
Vincenzo Rochira,Antonio R. M. Granata,Bruno Madeo,Lucia Zirilli,Giuseppina Rossi,Cesare Carani +5 more
TL;DR: The continuing increase in data obtained, and recent discoveries in this area will enable a better understanding of male physiology; these, in turn, will have important clinical implications.