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Coordination chemistry of metals in medicine: target sites for bismuth

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TLDR
Bismuth compounds are used for the treatment of gastrointestinal disorders and may also be useful for other diseases as discussed by the authors, however, they exhibit a highly variable coordination number (3-10) and often an irregular coordination geometry.
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This article is published in Coordination Chemistry Reviews.The article was published on 1999-05-01. It has received 249 citations till now. The article focuses on the topics: Coordination geometry & Coordination complex.

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Targeted Drug Delivery via the Transferrin Receptor-Mediated Endocytosis Pathway

TL;DR: The OX26 monoclonal antibody against the rat transferrin receptor offers great promise in the delivery of therapeutic agents across the blood-brain barrier to the brain and serves as a potential alternative to viral vector for gene therapy.
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New metal complexes as potential therapeutics.

TL;DR: Biological carriers conjugated to cisplatin analogs have improved specificity for tumor tissue, thereby reducing side effects and drug resistance, and metal-based chemotherapeutic compounds have the potential to modulate the biological properties of superoxide anion and nitric oxide.
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Platinum complexes as anticancer agents

TL;DR: This review focuses on recent advances in developing platinum anticancer agents with an emphasis on platinum coordination complexes, which exhibit promising pharmacological properties.
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Novel urea assisted hydrothermal synthesis of hierarchical BiVO4/Bi2O2CO3 nanocomposites with enhanced visible-light photocatalytic activity

TL;DR: In this article, a novel hydrothermal approach is developed for the first time to synthesize hierarchical BiVO4/Bi2O2CO3 nanocomposites with reactive crystalline facets using urea as a morphology mediator.
References
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Journal ArticleDOI

Metalle in Biologie und Medizin, III. Bismutlactat: Darstellung und Strukturchemie eines Hydroxycarboxylat‐Komplexes

TL;DR: In this paper, bismuth (S)-lactate was synthesized and structurally characterized (single-crystal X-ray diffraction), exploiting the versatile coordination chemistry of carboxylate groups (chelating and bridging ligands).
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Disposition of bismuth in the rat. I. Red blood cell and plasma protein binding.

TL;DR: In the concentration range studied, bismuth was associated primarily with the red blood cell fraction of whole blood obtained from male Sprague Dawley rats and the data indicated that binding to proteins was of moderate affinity, and in whole blood it was present primarily in the redBlood cell compartment.
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Bi-Sr-Ca-Cu-O superconducting films fabricated using metal alkoxides

TL;DR: In this article, a dip-coating solution using a mixed alkoxide solution, insoluble Cu and Bi alkoxides were dissolved by modification with 2-dimethylaminoethanol and formation of a double alkoxide, respectively.
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