Journal ArticleDOI
Coordination chemistry of metals in medicine: target sites for bismuth
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TLDR
Bismuth compounds are used for the treatment of gastrointestinal disorders and may also be useful for other diseases as discussed by the authors, however, they exhibit a highly variable coordination number (3-10) and often an irregular coordination geometry.About:
This article is published in Coordination Chemistry Reviews.The article was published on 1999-05-01. It has received 249 citations till now. The article focuses on the topics: Coordination geometry & Coordination complex.read more
Citations
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Targeted Drug Delivery via the Transferrin Receptor-Mediated Endocytosis Pathway
TL;DR: The OX26 monoclonal antibody against the rat transferrin receptor offers great promise in the delivery of therapeutic agents across the blood-brain barrier to the brain and serves as a potential alternative to viral vector for gene therapy.
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Drug delivery via the transferrin receptor-mediated endocytosis pathway
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New metal complexes as potential therapeutics.
TL;DR: Biological carriers conjugated to cisplatin analogs have improved specificity for tumor tissue, thereby reducing side effects and drug resistance, and metal-based chemotherapeutic compounds have the potential to modulate the biological properties of superoxide anion and nitric oxide.
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Platinum complexes as anticancer agents
TL;DR: This review focuses on recent advances in developing platinum anticancer agents with an emphasis on platinum coordination complexes, which exhibit promising pharmacological properties.
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Novel urea assisted hydrothermal synthesis of hierarchical BiVO4/Bi2O2CO3 nanocomposites with enhanced visible-light photocatalytic activity
TL;DR: In this article, a novel hydrothermal approach is developed for the first time to synthesize hierarchical BiVO4/Bi2O2CO3 nanocomposites with reactive crystalline facets using urea as a morphology mediator.
References
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Journal ArticleDOI
Crystal Structure of Cd,Zn Metallothionein
TL;DR: The anomalous scattering data from five Cd in the native protein were used to determine the crystal structure of cadmium, zinc (Cd,Zn) metallothionein isoform II from rat liver, and the structure of a 4-Cd cluster was solved by direct methods.
Journal ArticleDOI
Pharmacokinetics and toxicity of bismuth compounds.
Slikkerveer A,de Wolff Fa +1 more
TL;DR: Bismuth encephalopathy occurred in France as an epidemic of toxicity and was associated with the intake of inorganic salts including bismuth subnitrate, subcarbonate and subgallate and the use of dimercaprol as an antidote has produced reports of both positive and negative findings.
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Campylobacter pyloridis and Gastritis
TL;DR: The canaliculi of parietal cells were sometimes invaded, an occurrence suggesting that the organisms were acid tolerant; and in some specimens, infiltration with polymorphs, lymphocytes, and plasma cells was seen in association with the bacteria.
Journal Article
Prevention of lethal and renal toxicity of cis-diamminedichloroplatinum(II) by induction of metallothionein synthesis without compromising its antitumor activity in mice.
TL;DR: A correlation between the protective effect of pretreatment with bismuth nitrate against cis-DDP toxicity and the preinduced MT levels in the kidney was observed, resulting in more efficient utilization of this anticancer drug.
Related Papers (5)
Bismuth compounds and preparations with biological or medicinal relevance.
Glen G. Briand,Neil Burford +1 more