Cost-effective synthesis of 2D molybdenum disulfide (MoS2) nanocrystals: An exploration of the influence on cellular uptake, cytotoxicity, and bio-imaging
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TLDR
In this paper , a simple and economical method for synthesizing the luminescent nanocrystals MoS2 using the hydrothermal technique was proposed, which can selectively target and destroy lung cancer cells, especially drug-resistant cells.Abstract:
Ultrasmall MoS2 nanocrystals have unique optoelectronic and catalytic properties that have acquired significant attraction in many areas. We propose here a simple and economical method for synthesizing the luminescent nanocrystals MoS2 using the hydrothermal technique. In addition, the synthesized MoS2 nanocrystals display photoluminescence that is tunable according to size. MoS2 nanocrystals have many advantages, such as stable dispersion, low toxicity and luminescent characteristics, offering their encouraging applicability in biomedical disciplines. In this study, human lung cancer epithelial cells (A549) are used to assess fluorescence imaging of MoS2 nanocrystals. MTT assay, trypan blue assay, flow cytometry and fluorescence imaging results have shown that MoS2 nanocrystals can selectively target and destroy lung cancer cells, especially drug-resistant cells (A549). read more
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Synthesis, characterization and stability study of aqueous MPA capped CuInS2/ZnS core/shell nanoparticles
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Biosafety of inorganic nanomaterials for theranostic applications
TL;DR: In this paper , the progress and challenges of the development of biocompatible inorganic nanomaterials for theranostic applications were discussed, with appropriate precautions on the biosafe condition to be administered.
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A simple two-step strategy to synthesize defect-rich MoS2 nanocrystals for enhanced electrochemical hydrogen evolution
TL;DR: In this paper , the dispersion of bulk MoS2 in the aqueous phase was increased with a surfactant (sodium dodecyl sulfate), which reduced the exfoliation time and enhanced the exporters ability to produce layered MoS 2 nanosheets.
References
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Drug Delivery with PEGylated MoS2 Nano‐sheets for Combined Photothermal and Chemotherapy of Cancer
Teng Liu,Chao Wang,Xing Gu,Hua Gong,Liang Cheng,Xiaoze Shi,Liangzhu Feng,Baoquan Sun,Zhuang Liu +8 more
TL;DR: MoS2 nanosheets functionalized with poly-ethylene glycol are for the first time used as a multifunctional drug delivery system with high drug loading capacities achieving excellent synergistic anti-tumor effect upon systemic administration.
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Two-Dimensional Materials in Biosensing and Healthcare: From In Vitro Diagnostics to Optogenetics and Beyond
Adam Bolotsky,Derrick Butler,Chengye Dong,Katy S. Gerace,Nicholas R. Glavin,Christopher Muratore,Joshua A. Robinson,Aida Ebrahimi +7 more
TL;DR: A survey of the recent reports on the applications of 2D materials in biosensing and other emerging healthcare areas, ranging from wearable technologies to optogenetics to neural interfacing is provided.
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Capturing functional two-dimensional nanosheets from sandwich-structure vermiculite for cancer theranostics.
Xiaoyuan Ji,Lanlan Ge,Chuang Liu,Zhongmin Tang,Yufen Xiao,Wei Chen,Zhouyue Lei,Wei Gao,Sara Blake,Diba De,Bingyang Shi,Xiaobing Zeng,Na Kong,Xingcai Zhang,Wei Tao +14 more
TL;DR: In this paper, a universal wet-chemical exfoliation method based on alkali etching was proposed to capture the ultrathin and biocompatible 2D functional core layers (FCLs) sandwiched between two identical tetrahedral layers (SiO2 and Al2O3) from vermiculite.
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Intracellular Mechanistic Understanding of 2D MoS2 Nanosheets for Anti-Exocytosis-Enhanced Synergistic Cancer Therapy
Xianbing Zhu,Xiaoyuan Ji,Na Kong,Na Kong,Yunhan Chen,Morteza Mahmoudi,Xiao-Ding Xu,Li Ding,Wei Tao,Wei Tao,Ting Cai,Yujing Li,Tian Gan,Austin Barrett,Zameer Bharwani,Hongbo Chen,Omid C. Farokhzad +16 more
TL;DR: This is the first systematic experimental report on the nano-bio interaction of 2D nanomaterials in cells and their application for anti-exocytosis-enhanced synergistic cancer therapy.
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Biomedical Applications of Graphene Nanomaterials and Beyond
Krishanu Ghosal,Kishor Sarkar +1 more
TL;DR: This review will highlight the various synthesis procedures of graphene family nanomaterials including graphene oxide, reduced graphene oxide (rGO), and graphene quantum dots (GQDs) as well as their biomedical applications, and outline the future perspective and current challenges of graphene nanommaterials for clinical applications.