Delusions in first-episode psychosis: Principal component analysis of twelve types of delusions and demographic and clinical correlates of resulting domains
TLDR
The results support considering delusions as varied experiences with varying prevalences and correlates, and ascertained a general relationship between different childhood adversities and delusional themes, and a specific relationship between Somatic Delusions and childhood neglect.Abstract:
Although delusions represent one of the core symptoms of psychotic disorders, it is remarkable that few studies have investigated distinct delusional themes. We analyzed data from a large sample of first-episode psychosis patients (n=245) to understand relations between delusion types and demographic and clinical correlates. First, we conducted a principal component analysis (PCA) of the 12 delusion items within the Scale for the Assessment of Positive Symptoms (SAPS). Then, using the domains derived via PCA, we tested a priori hypotheses and answered exploratory research questions related to delusional content. PCA revealed five distinct components: Delusions of Influence, Grandiose/Religious Delusions, Paranoid Delusions, Negative Affect Delusions (jealousy, and sin or guilt), and Somatic Delusions. The most prevalent type of delusion was Paranoid Delusions, and such delusions were more common at older ages at onset of psychosis. The level of Delusions of Influence was correlated with the severity of hallucinations and negative symptoms. We ascertained a general relationship between different childhood adversities and delusional themes, and a specific relationship between Somatic Delusions and childhood neglect. Moreover, we found higher scores on Delusions of Influence and Negative Affect Delusions among cannabis and stimulant users. Our results support considering delusions as varied experiences with varying prevalences and correlates.read more
Citations
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The revised Green et al., Paranoid Thoughts Scale (R-GPTS): psychometric properties, severity ranges, and clinical cut-offs
Daniel Freeman,Bao Sheng Loe,David Kingdon,Helen Startup,Andrew Molodynski,Laina Rosebrock,Laina Rosebrock,Poppy Brown,Bryony Sheaves,Bryony Sheaves,Felicity Waite,Felicity Waite,Jessica C. Bird,Jessica C. Bird +13 more
TL;DR: The Revised-GPTS is a more precise measure, has excellent psychometric properties, and is recommended for future studies of paranoia.
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Primary and substance-induced psychotic disorders in methamphetamine users
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Benjamin Buck,Kevin A. Hallgren,Emily A. Scherer,Rachel Brian,Rui Wang,Weichen Wang,Andrew T. Campbell,Tanzeem Choudhury,Marta Hauser,John M. Kane,Dror Ben-Zeev +10 more
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Types, prevalence and gender differences of childhood trauma in first-episode psychosis. What is the evidence that childhood trauma is related to symptoms and functional outcomes in first episode psychosis? A systematic review
Regina Vila-Badia,Anna Butjosa,Núria Del Cacho,Clara Serra-Arumí,Marina Esteban-Sanjusto,Susana Ochoa,Judith Usall +6 more
TL;DR: FEP have a high prevalence of CT and its relationship with symptoms and functional outcomes indicates its importance within treatment, which suggests the importance of creating and implementing specific interventions and personalized therapies addressed to work through their past traumatic experiences to improve their quality of live and their prognosis.
References
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