Journal ArticleDOI
Dementia Three Months After Stroke Baseline Frequency and Effect of Different Definitions of Dementia in the Helsinki Stroke Aging Memory Study (SAM) Cohort
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TLDR
The findings question the validity of current criteria for dementia in the setting of cerebrovascular disease and emphasize the need for further debate and studies to refine the categories of cognitive impairment related to cerebroVascular disease.Abstract:
Background and Purpose Vascular dementia is a common cause of dementia, and cerebrovascular disease is related to a higher risk of dementia. The frequency of dementia associated with ischemic stroke and the effects of different definitions of dementia in the diagnosis are still incompletely known. We evaluated the frequency of cognitive decline and dementia 3 months after ischemic stroke in a large stroke cohort. Methods Our cohort consisted of consecutively admitted ischemic stroke patients (n=486) aged 55 to 85 years in the Helsinki (Finland) Stroke Aging Memory Study (SAM). Subjects were assessed by structured medical, neurological, and radiological examinations and interview with a close informant, as well as by the Mini-Mental State Examination and detailed clinical mental status examination of defined cognitive domains. The criteria for dementia were those of the Diagnostic and Statistical Manual of Mental Disorders (DSM) (DSM-III, DSM-III-R, and DSM-IV), the National Institute of Neurological Disor...read more
Citations
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Journal ArticleDOI
National Institute of Neurological Disorders and Stroke–Canadian Stroke Network Vascular Cognitive Impairment Harmonization Standards
Vladimir Hachinski,Costantino Iadecola,R. C. Petersen,Monique M.B. Breteler,David L. Nyenhuis,Sandra E. Black,William J. Powers,Charles DeCarli,José G. Merino,Raj N. Kalaria,Harry V. Vinters,David M. Holtzman,Gary A. Rosenberg,Martin Dichgans,John R. Marler,Gabrielle G. Leblanc +15 more
TL;DR: Using the same standards will help identify individuals in the early stages of cognitive impairment, will make studies comparable, and by integrating knowledge, will accelerate the pace of progress.
Journal ArticleDOI
Prevalence, incidence, and factors associated with pre-stroke and post-stroke dementia: a systematic review and meta-analysis.
TL;DR: The strong association of post-stroke dementia with multiple strokes and the prognostic value of other stroke characteristics highlight the central causal role of stroke itself as opposed to the underlying vascular risk factors and, thus, the likely effect of optimum acute stroke care and secondary prevention in reducing the burden of dementia.
Book
Vascular Cognitive Impairment
John T. O'Brien,Timo Erkinjuntti,Barry Reisberg,Gustavo C. Román,Tohru Sawada,Leonardo Pantoni,John V. Bowler,Clive Ballard,Charles DeCarli,Philip B. Gorelick,Kenneth Rockwood,Alistair Burns,Serge Gauthier,Steven T. DeKosky +13 more
TL;DR: Findings from 5 large, randomized studies of the symptomatic treatment of probable and possible vascular dementia indicate that the presence of a cholinergic deficit is not required for the anticholinesterases to produce cognitive improvement, and so the cholin allergic hypothesis is neither necessary nor sufficient to explain the effects of these drugs.
Journal ArticleDOI
Effects of blood pressure lowering with perindopril and indapamide therapy on dementia and cognitive decline in patients with cerebrovascular disease.
Christophe Tzourio,Craig S. Anderson,Neil Chapman,Mark Woodward,Bruce Neal,Stephen MacMahon,John Chalmers +6 more
TL;DR: Findings further support the recommendation that blood pressure lowering with perindopril and indapamide therapy be considered for all patients with cerebrovascular disease.
Book ChapterDOI
Research criteria for subcortical vascular dementia in clinical trials.
Timo Erkinjuntti,Domenico Inzitari,Leonardo Pantoni,Anders Wallin,P. Scheltens,Kenneth Rockwood,Gustavo C. Roman,Helena C. Chui,David W. Desmond +8 more
TL;DR: In this paper, a modification of the NINDS-AIREN criteria was proposed for subcortical vascular dementia (VaD), which includes small vessel disease as the primary vascular etiology, lacunar infarct(s) and ischaemic white matter lesions as primary type of brain lesions.
References
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Journal ArticleDOI
“Mini-mental state”: A practical method for grading the cognitive state of patients for the clinician
Marshal F. Folstein,Marshal F. Folstein,Susan E B Folstein,Susan E B Folstein,Paul R. McHugh,Paul R. McHugh +5 more
TL;DR: A simplified, scored form of the cognitive mental status examination, the “Mini-Mental State” (MMS) which includes eleven questions, requires only 5-10 min to administer, and is therefore practical to use serially and routinely.
A practical method for grading the cognitive state of patients for the clinician
TL;DR: The Mini-Mental State (MMS) as mentioned in this paper is a simplified version of the standard WAIS with eleven questions and requires only 5-10 min to administer, and is therefore practical to use serially and routinely.
Journal ArticleDOI
Assessment of Older People: Self-Maintaining and Instrumental Activities of Daily Living
M. P. Lawton,Elmne M. Brody +1 more
TL;DR: Two scales first standardized on their own population are presented, one of which taps a level of functioning heretofore inadequately represented in attempts to assess everyday functional competence, and the other taps a schema of competence into which these behaviors fit.
Related Papers (5)
Vascular dementia Diagnostic criteria for research studies: Report of the NINDS‐AIREN International Workshop*
Gustavo C. Román,Thomas K. Tatemichi,T. Erkinjuntti,Jeffrey L. Cummings,Joseph C. Masdeu,J. H. Garcia,L. Amaducci,J. M. Orgogozo,A. Brun,Albert Hofman,D. M. Moody,M. D. O’Brien,T. Yamaguchi,Jordan Grafman,B. P. Drayer,D. A. Bennett,Marc Fisher,J. Ogata,E. Kokmen,F. Bermejo,Philip A. Wolf,P. B. Gorelick,K. L. Bick,A. K. Pajeau,M. A. Bell,Charles DeCarli,A. Culebras,Amos D. Korczyn,J. Bogousslavsky,A. Hartmann,P. Scheinberg +30 more