Book ChapterDOI
Design and Analysis of MEMS based Cantilever Sensor for the Detection of Cardiac Markers in Acute Myocardial Infarction
S. Vidhya,Lazar Mathew +1 more
- pp 810-812
TLDR
In this paper, a geometric variation of the cantilever was proposed to improve the sensitivity of the microcantilever and to eliminate the disadvantages while improving the sensitivity simultaneously.Abstract:
Piezo-resistive actuation of a microcantilever induced by biomolecular binding such as DNA hybridization and antibody-antigen binding is an important principle useful in biosensing applications. As the magnitude of the forces exerted is small, increasing the sensitivity of the microcantilever becomes critical. In this paper, we are considering to achieve this by geometric variation of the cantilever. The sensitivity of the cantilever was improved so that the device can sense the presence of antigen even if the magnitude of surfacestresses over the microcantilever was very small. We consider a ‘T-shaped’ cantilever that eliminates the disadvantages while improving the sensitivity simultaneously. Simulations for validation have been performed using Intellisuite software (a MEMS design and simulation package). The simulations reveal that the T-shaped microcantilever is almost as sensitive as a thin cantilever and has relatively very low buckling effect. Simulations also reveal that with an increase in thickness of the cantilever, there is a proportional decrease in the sensitivity.read more
Citations
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Journal ArticleDOI
Vortex Anemometer Using MEMS Cantilever Sensor
TL;DR: In this paper, a hybrid microelectromechanical system (MEMS) vortex flowmeter was used to detect frequency of vortices development in a 40mm-diameter tubular pipe.
Journal ArticleDOI
Micro-cantilevered MEMS Biosensor for Detection of Malaria Protozoan Parasites
TL;DR: In this article, an E-shaped model for micro cantilevered biosensor is designed using COMSOL multiphysics specifically for detection of Malaria protozoan parasites.
Theoretical Analysis of Laterally Vibrating Hammerhead Microcantilever Sensors in a Viscous Liquid
TL;DR: Zhang et al. as mentioned in this paper investigated the properties of symmetric hammerhead microcantilevers vibrating laterally in viscous liquid media, and the results showed that, with a fixed head area, the resulting resonance frequency and mass sensitivity will first increase and then decrease, because the total kinetic energy will first decrease and then increase.
Vortex Anemometer Using MEMS Cantilever Sensor
TL;DR: In this paper, a hybrid microelectromechanical system (MEMS) vortex sensor was used to detect frequency of vortices development in a 40mm-diameter tubular pipe.
References
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Journal Article
Comparison of myoglobin, creatine kinase-MB, and cardiac troponin I for diagnosis of acute myocardial infarction
TL;DR: Results of this study show that cTnI is an effective marker for the retrospective diagnosis of AMI, and consideration should be given to its use in place of CK-MB.
Journal ArticleDOI
Simulation and design of piezoelectric microcantilever chemical sensors
TL;DR: In this article, an analytical modeling of a piezoelectric multi-layer cantilever used as a micro-electro-mechanical-system (MEMS) chemical sensor is presented.
Journal ArticleDOI
A flow-through amperometric sensor for micro-analytical systems
TL;DR: The performance of the flow-through amperometric sensor based on semi-permeable dialysis tubing implemented in silicon is presented in this paper, where the sensor is designed in the form to be an integral component of a lab-on-a-chip systems and it has been successfully incorporated into an integrated microdialysis system.
Journal ArticleDOI
Diagnostic value of heart fatty acid binding protein and myoglobin in patients admitted with chest pain.
TL;DR: Myoglobin and hFABP provide little clinical value when measured on admission in patients presenting with chest pain, and both performed poorly in those patients who were cTnI negative on admission.
Related Papers (5)
Sensitivity Analysis of Rectangular Microcantilever Structure with Piezoresistive Detection Technique Using Coventorware FEA
K. Neethu,K. J. Suja +1 more