Journal ArticleDOI
Design and characterizations of novel biodegradable ternary Zn-based alloys with IIA nutrient alloying elements Mg, Ca and Sr
TLDR
In this paper, three IIA essential nutrient elements Mg, Ca and Sr and hot rolling and hot-extrusion thermal deformations have been applied to overcome the drawback of pure Zn and benefit the biocompatibility of Zn-based potential implants.About:
This article is published in Materials & Design.The article was published on 2015-10-15. It has received 207 citations till now.read more
Citations
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Journal ArticleDOI
Biodegradable Metals for Cardiovascular Stents: from Clinical Concerns to Recent Zn‐Alloys
Patrick K. Bowen,Emily R. Shearier,Shan Zhao,Roger J. Guillory,Feng Zhao,Jeremy Goldman,Jaroslaw Drelich +6 more
TL;DR: A third class of metallic bioabsorbable materials that are based on zinc has been introduced in the last few years and demonstrates the potential for an absorbable metallic stent with the mechanical and biodegradation characteristics required for optimal stent performance.
Journal ArticleDOI
Novel Zn-based alloys for biodegradable stent applications: Design, development and in vitro degradation.
Ehsan Mostaed,Malgorzata Urszula Sikora-Jasinska,Ali Mostaed,Sergio Loffredo,Ali Gökhan Demir,Barbara Previtali,Diego Mantovani,Richard Beanland,Maurizio Vedani +8 more
TL;DR: Zn-0.5Mg is the most promising material for stent applications with a good combination of strength, ductility, strain hardening exponent and an appropriate rate of loss of mechanical integrity during degradation.
Journal ArticleDOI
Recent advances in bulk metallic glasses for biomedical applications
Huafang Li,Yufeng Zheng +1 more
TL;DR: The present work reviewed the recent developments and advances of biomedical BMGs, including Ti- based, Zr-based, Fe-based and Mg-based BMG alloying systems, and the possible solution to the BMG size limitation, the brittleness of B MGs has been proposed.
Journal ArticleDOI
The influence of alloying and fabrication techniques on the mechanical properties, biodegradability and biocompatibility of zinc: A comprehensive review.
TL;DR: This review offers an up-to-date and comprehensive review of the influence of alloying and fabrication technique on mechanical properties, biodegradability and biocompatibility of Zn.
Journal ArticleDOI
Zinc-based alloys for degradable vascular stent applications.
Ehsan Mostaed,Ehsan Mostaed,Malgorzata Urszula Sikora-Jasinska,Jaroslaw Drelich,Maurizio Vedani +4 more
TL;DR: This review summarizes recent progress made in developing Zn alloys for vascular stenting application and critically surveys the zinc alloys developed since 2013 from metallurgical and biodegradation points of view.
References
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Journal ArticleDOI
Physiological functions of mineral macronutrients.
TL;DR: Important progress has been made in identifying transport and regulatory mechanisms for macronutrients and the mechanisms of uptake and distribution and the main physiological roles of each nutrient will be discussed.
Journal ArticleDOI
Physiological functions of mineral micronutrients (Cu, Zn, Mn, Fe, Ni, Mo, B, Cl).
Robert Hänsch,Ralf R. Mendel +1 more
TL;DR: This review focuses on the major functions of mineral micronutrients, mostly in cases where they were shown as constituents of proteins, making a selection and highlighting some functions in more detail.
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Trace elements in human physiology and pathology: zinc and metallothioneins.
H Tapiero,Kenneth D. Tew +1 more
TL;DR: Zinc ions exist primarily in the form of complexes with proteins and nucleic acids and participate in all aspects of intermediary metabolism, transmission and regulation of the expression of genetic information, storage, synthesis and action of peptide hormones and structural maintenance of chromatin and biomembranes.
Journal ArticleDOI
Zinc Exhibits Ideal Physiological Corrosion Behavior for Bioabsorbable Stents
TL;DR: Not only is zinc a physiologically relevant metal with behavior that promotes healthy vessels, but it combines the best behaviors of both current bioabsorbable stent materials: iron and magnesium.
Journal ArticleDOI
Mechanical and corrosion properties of newly developed biodegradable Zn-based alloys for bone fixation
TL;DR: The corrosion rates of the Zn-Mg alloys were determined to be significantly lower than those of Mg and AZ91HP alloys and possible zinc doses and toxicity were estimated from the corrosion behavior of the zinc alloys.