Detection of viruses in myocardial tissues by polymerase chain reaction. evidence of adenovirus as a common cause of myocarditis in children and adults.
Neil E. Bowles,Jiyuan Ni,Debra L. Kearney,Matthias Pauschinger,Heinz-Peter Schultheiss,Robert E. Mccarthy,Joshua M. Hare,J. Timothy Bricker,Karla R. Bowles,Jeffrey A. Towbin +9 more
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TLDR
Polymerase chain reaction identified adenovirus as the most common virus in the myocardium of children and adults with myocarditis and DCM, and enteroviruses are also found in these patients.About:
This article is published in Journal of the American College of Cardiology.The article was published on 2003-08-06 and is currently open access. It has received 613 citations till now. The article focuses on the topics: Enterovirus & Myocarditis.read more
Citations
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Current state of knowledge on aetiology, diagnosis, management, and therapy of myocarditis: a position statement of the European Society of Cardiology Working Group on Myocardial and Pericardial Diseases.
Alida L.P. Caforio,S. Pankuweit,Eloisa Arbustini,Cristina Basso,Juan Ramón Gimeno-Blanes,Stephan B. Felix,Michael Fu,Tiina Heliö,Stephane Heymans,Roland Jahns,Karin Klingel,Aleš Linhart,Bernhard Maisch,William J. McKenna,Jens Mogensen,Y. M. Pinto,Arsen D. Ristić,Heinz-Peter Schultheiss,Hubert Seggewiss,Luigi Tavazzi,Gaetano Thiene,Ali Yilmaz,Philippe Charron,Perry M. Elliott +23 more
TL;DR: The aims are to bridge the gap between clinical and tissue-based diagnosis, to improve management and provide a common reference point for future registries and multicentre randomised controlled trials of aetiology-driven treatment in inflammatory heart muscle disease.
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The role of endomyocardial biopsy in the management of cardiovascular disease: A Scientific Statement from the American Heart Association, the American College of Cardiology, and the European Society of Cardiology Endorsed by the Heart Failure Society of America and the Heart Failure Association of the European Society of Cardiology
Leslie T. Cooper,Kenneth L. Baughman,Arthur M. Feldman,Andrea Frustaci,Mariell Jessup,Uwe Kühl,Glenn N. Levine,Jagat Narula,Randall C. Starling,Jeffrey A. Towbin,Renu Virmani +10 more
TL;DR: The ultimate intent of this document is to provide an understanding of the range of acceptable approaches for the use of EMB while recognizing that individual patient care decisions depend on factors not well reflected in the published literature, such as local availability of specialized facilities, cardiovascular pathology expertise, and operator experience.
Journal ArticleDOI
The role of endomyocardial biopsy in the management of cardiovascular disease: a scientific statement from the American Heart Association, the American College of Cardiology, and the European Society of Cardiology.
Leslie T. Cooper,Kenneth L. Baughman,Arthur M. Feldman,Andrea Frustaci,Mariell Jessup,Uwe Kühl,Glenn N. Levine,Jagat Narula,Randall C. Starling,Jeffrey A. Towbin,Renu Virmani +10 more
TL;DR: The ultimate intent of this document is to provide an understanding of the range of acceptable approaches for the use of EMB while recognizing that individual patient care decisions depend on factors not well reflected in the published literature, such as local availability of specialized facilities, cardiovascular pathology expertise, and operator experience.
Journal ArticleDOI
Presentation, Patterns of Myocardial Damage, and Clinical Course of Viral Myocarditis
Heiko Mahrholdt,Anja Wagner,Claudia C. Deluigi,Eva Maria Kispert,Stefan Hager,Gabriel Meinhardt,Holger Vogelsberg,Peter Fritz,Juergen Dippon,C.-Thomas Bock,Karin Klingel,Reinhard Kandolf,Udo Sechtem +12 more
TL;DR: The data indicate that PVB19 and HHV6 are the most important causes for viral myocarditis in Germany and that the clinical presentation is related to the type of virus.
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Diagnostic performance of cardiovascular magnetic resonance in patients with suspected acute myocarditis: comparison of different approaches
Hassan Abdel-Aty,Philipp Boyé,Anja Zagrosek,Ralf Wassmuth,Andreas Kumar,Daniel Messroghli,Petra Bock,Rainer Dietz,Matthias G. Friedrich,Matthias G. Friedrich,Jeanette Schulz-Menger +10 more
TL;DR: A combined CMR approach using T2-weighted imaging, early and late gadolinium enhancement, provides a high diagnostic accuracy and is a useful tool in the diagnosis and assessment of patients with suspected acute myocarditis.
References
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Isolation of a Common Receptor for Coxsackie B Viruses and Adenoviruses 2 and 5
Jeffrey M. Bergelson,Jennifer Cunningham,Gustavo Droguett,Evelyn A. Kurt-Jones,Anita Krithivas,Jeong S. Hong,Marshall S. Horwitz,Richard L. Crowell,Robert W. Finberg +8 more
TL;DR: Identification of CAR as a receptor for these two unrelated and structurally distinct viral pathogens is important for understanding viral pathogenesis and has implications for therapeutic gene delivery with adenovirus vectors.
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Sudden death in young athletes
TL;DR: In this series of young athletes, sudden death was usually due to structural cardiovascular disease, and hypertrophic cardiomyopathy was a frequent cause of sudden death; atherosclerotic coronary heart disease was relatively uncommon.
Journal Article
Myocarditis. A histopathologic definition and classification.
HT Aretz,ME Billingham,William D. Edwards,SM Factor,John T. Fallon,Jr Jj Fenoglio,E. G. J. Olsen,Frederick J. Schoen +7 more
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HCAR and MCAR: The human and mouse cellular receptors for subgroup C adenoviruses and group B coxsackieviruses
TL;DR: Western blots using antibodies that inhibit virus binding to either the human or mouse CVB receptors detected 46-kDa proteins in HCAR- and MCAR-transfected cells, respectively and confirmed that the isolated cDNAs encode the receptors for the subgroup C Ad and CVB.
Journal ArticleDOI
Sudden death in young athletes.
TL;DR: In this series of young athletes, sudden death was usually due to structural cardiovascular disease, and hypertrophic cardiomyopathy was a frequent cause of sudden death; atherosclerotic coronary heart disease was relatively uncommon.