Journal ArticleDOI
Determination of free and conjugated catecholamines and l-3,4-dihydroxyphenylalanine in plasma and urine: evidence for a catechol-O-methyltransferase inhibitor in uraemia
TLDR
This assay led to the discovery of a dialyzable factor in the plasma of chronic uraemic patients which inhibits catechol-O-methyltransferase activity in vitro and its implication in physiopathological disorders remain to be established.About:
This article is published in Clinica Chimica Acta.The article was published on 1981-09-24. It has received 30 citations till now. The article focuses on the topics: Dihydroxyphenylalanine & Catechol-O-methyl transferase.read more
Citations
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Journal ArticleDOI
A more sensitive and specific radioenzymatic assay for catecholamines
TL;DR: This modification of the catechol-O-methyltransferase (COMT) based radioenzymatic assay for norepinephrine (NE) and epinephrine (E) improves sensitivity, selectivity and eliminates many inhibitors of COMT.
Advances in Catecholamine and MetaboliteMeasurementsfor Diagnosisof Pheochromocytoma
TL;DR: Assessment of catecholamine production and excretion is important in the laboratory detection of pheochromocytoma and in monitoring the completeness of tumor excision as well as the possibility of recurrence.
Journal ArticleDOI
Treatment of Refractory Ascites Using Transjugular Intrahepatic Portosystemic Shunt (TIPS) (A Caution)
J P Martinet,Daphna Fenyves,L Legault,Louise Roy,M P Dufresne,L. Spahr,M Lafortune,Gilles Pomier-Layrargues +7 more
TL;DR: TIPS can control refractory ascites in a majority of patients but is associated with a high rate of chronic disabling HE and the survival rate is poor; Randomized trials are needed to evaluate the exact role of TIPS in the management of refractors.
Journal ArticleDOI
Plasma free, sulfo- and glucuro-conjugated catecholamines in uremic patients.
TL;DR: The metabolism of catecholamines in non-selected patients with chronic renal failure and under hemodialysis was studied by measuring the concentration of plasma free, sulfo- and glucuroconjugated CA, dopamine, norepinephrine, and epinephrine; a statistically significant increase in free DA and free NE concentration in CRFh is demonstrated.
Journal ArticleDOI
Biogenic amines and their metabolites in body fluids of normal, psychiatric and neurological subjects.
TL;DR: Tables of normal values and the methods used to obtain them should prove to be useful as a reference source for benchmark amine and metabolite concentrations and for successful analytical procedures for their chromatographic separation, detection and quantification.
References
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Journal ArticleDOI
Determination of serum proteins by means of the biuret reaction.
TL;DR: An investigation of the biochemical changes following experimental liver injury felt the need of a simple, rapid, and accurate method for determining the protein fractions in small amounts of serum and began with Kingsley’s biuret procedure.
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Simultaneous single isotope radioenzymatic assay of plasma norepinephrine, epinephrine and dopamine.
TL;DR: Modification of the original single isotope radioenzymatic assay of Passon and Peuler permits the direct and simultaneous analysis of norepinephrine, epinephrine and dopamine in plasma samples of 50 μl or less.
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Enzymatic O-methylation of epinephrine and other catechols.
Julius Axelrod,Robert Tomchick +1 more
TL;DR: The properties of an enzyme that transfers the methyl group of S-adenosylmethionine to the hydroxyl group in position 3 of epinephrine and other catechols are described.
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Simultaneous radioenzymatic determination of plasma and tissue adrenaline, noradrenaline and dopamine within the femtomole range.
Mosé Da Prada,Gerhard Zürcher +1 more
TL;DR: A radiometric-enzymatic assay for measuring simultaneously femtomole quantities of adrenaline, noradrenaline and dopamine has been developed and promises to be a valid alternative to the gas chromatography-mass spectrometry technique.
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Catecholamines in fetal and newborn rat brain.
Joseph T. Coyle,D. Henry +1 more
TL;DR: An investigation of the effects of reserpine, pheniprazine, α‐methyl‐para‐tyrosine, diethyldithiocarbamate and l ‐DOPA on the levels of dopamine and norepinephrine in the brains of the 18‐day gestational fetus indicated that the levelsof these neurotransmitters are under controls similar to those known to occur in the brain of the adult rat.