Journal ArticleDOI
Simultaneous single isotope radioenzymatic assay of plasma norepinephrine, epinephrine and dopamine.
TLDR
Modification of the original single isotope radioenzymatic assay of Passon and Peuler permits the direct and simultaneous analysis of norepinephrine, epinephrine and dopamine in plasma samples of 50 μl or less.About:
This article is published in Life Sciences.The article was published on 1977-09-01. It has received 2028 citations till now. The article focuses on the topics: Norepinephrine (medication).read more
Citations
More filters
Journal ArticleDOI
Stress hormones: Their interaction and regulation.
Julius Axelrod,Terry Reisine +1 more
TL;DR: Together these agents appear to determine the complex physiologic responses to a variety of stressors.
Journal ArticleDOI
Sympathetic overactivity in patients with chronic renal failure.
Richard L. Converse,Tage N. Jacobsen,Robert D. Toto,Charles M.T. Jost,Frank Cosentino,Fetnat M. Fouad-Tarazi,Ronald G. Victor,Ronald G. Victor +7 more
TL;DR: Chronic renal failure may be accompanied by reversible sympathetic activation, which appears to be mediated by an afferent signal arising in the failing kidneys.
Journal ArticleDOI
Norepinephrine spillover to plasma in patients with congestive heart failure: evidence of increased overall and cardiorenal sympathetic nervous activity.
TL;DR: There is marked regional variation, inapparent from measurements of plasma norepinephrine concentration, in sympathetic nerve activity in patients with congestive heart failure.
Journal ArticleDOI
Concurrent morning increase in platelet aggregability and the risk of myocardial infarction and sudden cardiac death.
Geoffrey H. Tofler,Damian Brezinski,Andrew I. Schafer,Charles A. Czeisler,John D. Rutherford,Stefan N. Willich,Ray E. Gleason,Gordon H. Williams,James E. Muller +8 more
TL;DR: The period from 6 to 9 a.m. was the only interval in the 24-hour period during which platelet aggregability increased significantly, and in vitro platelet responsiveness to either adenosine diphosphate or epinephrine was lower.
Journal ArticleDOI
Tonic vasomotor control by the rostral ventrolateral medulla: effect of electrical or chemical stimulation of the area containing C1 adrenaline neurons on arterial pressure, heart rate, and plasma catecholamines and vasopressin
Christopher A. Ross,David A. Ruggiero,Dong H. Park,Tong H. Joh,Alan F. Sved,Julio Fernandez-Pardal,Julio Fernandez-Pardal,Juan M. Saavedra,Donald J. Reis +8 more
TL;DR: Neurons within the RVL, most probably C1 adrenaline- synthesizing neurons, exert an excitatory influence on sympathetic vasomotor fibers, the adrenal medulla, and the posterior pituitary, as well as under tonic inhibitory control, in part via GABAergic mechanisms.
References
More filters
Journal ArticleDOI
Enzymatic O-methylation of epinephrine and other catechols.
Julius Axelrod,Robert Tomchick +1 more
TL;DR: The properties of an enzyme that transfers the methyl group of S-adenosylmethionine to the hydroxyl group in position 3 of epinephrine and other catechols are described.
Journal ArticleDOI
Simultaneous radioenzymatic determination of plasma and tissue adrenaline, noradrenaline and dopamine within the femtomole range.
Mosé Da Prada,Gerhard Zürcher +1 more
TL;DR: A radiometric-enzymatic assay for measuring simultaneously femtomole quantities of adrenaline, noradrenaline and dopamine has been developed and promises to be a valid alternative to the gas chromatography-mass spectrometry technique.
Journal ArticleDOI
Norepinephrine and Epinephrine Release and Adrenergic Mediation of Smoking-Associated Hemodynamic and Metabolic Events
TL;DR: Since significant smoking-associated increments, in pulse rate, blood pressure and blood lactate/pyruvate ratio, preceded measurable increments in plasma catecholamine concentrations, but were adrenergically mediated, these changes should be attributed to norepinephrine released locally from adrenergic axon terminals within the tissues rather than to increments in circulating catechlamines.
Journal ArticleDOI
Catecholamines in fetal and newborn rat brain.
Joseph T. Coyle,D. Henry +1 more
TL;DR: An investigation of the effects of reserpine, pheniprazine, α‐methyl‐para‐tyrosine, diethyldithiocarbamate and l ‐DOPA on the levels of dopamine and norepinephrine in the brains of the 18‐day gestational fetus indicated that the levelsof these neurotransmitters are under controls similar to those known to occur in the brain of the adult rat.
Journal ArticleDOI
A simplified radiometric assay for plasma norepinephrine and epinephrine.
Philip G. Passon,Jacob D. Peuler +1 more
TL;DR: The plasma norepinephrine and epinephrine assay, when compared to currently available methods, provides a substantial decrease in the assay time while providing a 10-fold increase in sensitivity which allows the analysis to be performed on 0.75 ml or less of plasma.
Related Papers (5)
Simultaneous radioenzymatic determination of plasma and tissue adrenaline, noradrenaline and dopamine within the femtomole range.
Mosé Da Prada,Gerhard Zürcher +1 more