Journal ArticleDOI
Dietary regulation of pancreatic protein synthesis. I. Rapid and specific modulation of enzyme synthesis by changes in dietary composition.
J.C. Dagorn,R.G. Lahaie +1 more
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TLDR
Exocrine pancreatic protein synthesis can be modulated as early as 2 h after refeeding and this modulation is followed by adaptative changes in pancreatic enzyme content.About:
This article is published in Biochimica et Biophysica Acta.The article was published on 1981-06-26. It has received 57 citations till now. The article focuses on the topics: Trypsinogen & Amylase.read more
Citations
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Journal ArticleDOI
Adaptation of the exocrine pancreas to diet.
TL;DR: The evidence supports a pretranslational mechanism of the adaptation of proteases, amylase, and lipase to their respective substrates and suggests potential translational mechanisms of other enzymes in these adaptations and suggests the possibility of multiple mechanisms of regulation by a single effector.
OtherDOI
Vertebrate Gastrointestinal System
William H. Karasov,Ian D. Hume +1 more
TL;DR: The sections in this article are: Matching Food Intake, Throughput, Breakdown, and Absorption: Integrative Models, Fermentation, andAbsorption, and Toward an Ecological Physiology of Food Exploitation.
Journal ArticleDOI
Two similar but nonallelic rat pancreatic trypsinogens. Nucleotide sequences of the cloned cDNAs.
TL;DR: The enzymes encoded by trypsinogen I and II mRNAs retain the key amino acid residues that determine the characteristic substrate cleavage preference of trypsins and, therefore, represent the rat counterparts of this digestive enzyme.
Journal ArticleDOI
Amino acid transport by small intestinal, hepatic, and pancreatic epithelia
TL;DR: This review will report on the transport systems for L--amino acids present in the plasma membrane of epithelial cells of the small intestine, liver, and pancreas and highlight somewhat different but complimentary aspects of the understanding of amino acid transport.
Journal ArticleDOI
A multidimensional case-control study of dietary, alcohol, and tobacco habits in alcoholic men with chronic pancreatitis.
TL;DR: It is concluded that the reasons alcoholic men develop chronic pancreatitis may be explained partly by dietary habits, the main predisposing or associated factor is a high caloric proportion of fat and protein intake.
References
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Journal ArticleDOI
Intracellular aspects of the process of protein synthesis
TL;DR: The title of the Nobel Lecture of George Palade (1 August, p. 347) should have been "Intracellular aspects of the process of protein secretion."
Journal ArticleDOI
A modified spectrophotometric determination of chymotrypsin, trypsin, and thrombin.
TL;DR: The spectrophotometric procedure proposed by Schwert and Takenaka has been modified and extended to include the application to N-benzoyl-L-tyrosine ethyl ester and α-p-toluenesulphonyl- L-arginine methyl ester, allowing the determination of traces of chymotrypsin in the presence of relatively large amounts of trypsin.
Journal ArticleDOI
On amylolytic enzymes; beta-amylase; activity assay and control of the absence of alpha-amylase.
G. Noelting,P. Bernfeld +1 more
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Variations de la teneur en enzymes du pancréas de rat en fonction de la composition des régimes
TL;DR: Enzyme determinations in homogenates of pancreas of rats fed on a balanced, a starch-rich, a casein-rich or a fat-rich diet suggest that the specific activity of amylase and chymotrypsinogen follows closely the starch and the casein content of the diet, respectively.
Journal ArticleDOI
Adaptation of rat pancreatic amylase and chymotrypsinogen to changes in diet.
TL;DR: Amylase synthesis in hypophysectomized rats was considerably depressed and unresponsibe to increased carbohydrate, and this effect could be partially relieved with hydrocortisone, corticosterone, or thyroxin, but not with growth hormone.
Related Papers (5)
Hormonal stimulation in the exocrine pancreas results in coordinate and anticoordinate regulation of protein synthesis.
J. Schick,H. Kern,G. Scheele +2 more