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Journal ArticleDOI

Dietary supplementation with Ethiopian pepper (Xylopia aethiopica) modulates angiotensin-I converting enzyme activity, antioxidant status and extenuates hypercholesterolemia in high cholesterol fed Wistar rats

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TLDR
The observed hypolipidemic, antihypertensive and hepatoprotective effects exhibited by ETP suggest its potentials to prevent lipid abnormalities and associated risk factors, and this could be attributed to its phenolic constituents.
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This article is published in PharmaNutrition.The article was published on 2018-03-01. It has received 9 citations till now. The article focuses on the topics: High cholesterol & Xylopia aethiopica.

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Journal ArticleDOI

Effect of p-coumaric acid on the erectogenic enzyme activities and non-protein thiol level in the penile tissue of normal and doxorubicin-induced oxidative stress male rat.

TL;DR: It is revealed that PCA is capable of causing inhibitory effects on the activities of enzymes, associated with oxidative stress‐induced erectile dysfunction (ED) and could also be used as an aphrodisiac agent in the management/treatment of ED.
Journal ArticleDOI

Horseradish (Moringa oleifera) seed and leaf inclusive diets modulates activities of enzymes linked with hypertension, and lipid metabolites in high-fat fed rats

TL;DR: Phenolic constituents of the horseradish leaf and seed were determined via high performance liquid chromatography (HPLC-DAD) and the result revealed that rats in HC group had higher cholesterol levels than normal control rats.
Book ChapterDOI

Role of Oxidative Stress in the Pathophysiology of Type 2 Diabetes and Cardiovascular Diseases

TL;DR: In this article, the authors examined the association of oxidative stress with hyperglycemia, insulin resistance, hyperinsulinemia, hypertension, hypercholesterolemia, and/or dyslipidemia.
Journal ArticleDOI

HPLC-DAD Phenolic Profiling and In Vitro Antioxidant Activities of Three Prominent Nigerian Spices

TL;DR: The XA methanolic extract demonstrated a high content of phenolic compounds and significant antioxidative properties, with prospective potency to prevent oxidative damage and promote better cardiovascular health.
Journal ArticleDOI

Diet Supplemented with Chrysophyllum albidum G. Don (Sapotaceae) Fruit Pulp Improves Reproductive Function in Hypertensive Male Rats.

TL;DR: In this article, the effect of diet supplemented with Chrysophyllum albidum fruit pulp (FP) on sperm parameters, reproductive hormones, and antioxidant markers in testes and epididymis of hypertensive rats was investigated.
References
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Journal ArticleDOI

Estimation of the Concentration of Low-Density Lipoprotein Cholesterol in Plasma, Without Use of the Preparative Ultracentrifuge

TL;DR: A method for estimating the cholesterol content of the serum low-density lipoprotein fraction (Sf0-20) is presented and comparison of this suggested procedure with the more direct procedure, in which the ultracentrifuge is used, yielded correlation coefficients of .94 to .99.
Journal ArticleDOI

Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction

TL;DR: Using this method, the liped peroxide level in the liver of rats suffering from carbon tetrachloride intoxication was investigated and was in good agreement with previously reported data obtained by measuring diene content.
Journal ArticleDOI

Tissue sulfhydryl groups

TL;DR: A water-soluble (at pH 8) aromatic disulfide [5,5′-dithiobis(2-nitrobenzoic acid] has been synthesized and shown to be useful for determination of sulfhydryl groups.
Book ChapterDOI

Analysis of total phenols and other oxidation substrates and antioxidants by means of folin-ciocalteu reagent

TL;DR: Aggregate analysis of this type is an important supplement to and often more informative than reems of data difficult to summarize from various techniques, such as high-performance liquid chromatography (HPLC) that separate a large number of individual compounds.
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