Journal ArticleDOI
Diminazene aceturate in the control of Trypanosoma evansi infection in cats.
A. S. da Silva,Régis Adriel Zanette,Patrícia Wolkmer,Mateus Matiuzzi da Costa,H.A. Garcia,Sonia Terezinha dos Anjos Lopes,Jânio Morais Santúrio,M.M.G. Teixeira,Silvia Gonzalez Monteiro +8 more
TLDR
The therapy used is effective in controlling T. evansi in cats andAlanine aminotransferase, gamma-glutamyltransferase, urea, and creatinine values remained within the normal physiological range in the treated cats.About:
This article is published in Veterinary Parasitology.The article was published on 2009-10-28. It has received 32 citations till now. The article focuses on the topics: Diminazene & Trypanosoma evansi.read more
Citations
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Journal ArticleDOI
Diminazene Diaceturate for Treatment of Chronic Cytauxzoon felis Parasitemia in Naturally Infected Cats
TL;DR: Dinazene diaceturate was unable to eliminate the pathogen or decrease parasite burden in healthy, chronically infected cats.
Chemotherapeutic agents against pathogenic animal trypanosomes
TL;DR: The aim of the present chapter is to review the current status of the therapeutic and prophylactic agents used for the control of pathogenic animal trypanosomes as well as the potential candidates that are tested nowadays as possible new trypanocides to be used in the next future.
Journal ArticleDOI
Failure of efficacy and adverse events associated with dose-intense diminazene diaceturate treatment of chronic Cytauxzoon felis infection in five cats
TL;DR: It is hypothesized that a dose-intensified regimen of diminazene could reduce or eliminate parasitemia from five domestic cats naturally infected with C felis and that Diminazene diaceturate cannot be recommended for elimination of the carrier state of C fel is infection.
Journal ArticleDOI
Pharmacokinetics of diminazene diaceturate in healthy cats
TL;DR: The pharmacokinetic profile of diminazene diaceturate in cats was characterized and it was found that this drug, if found to be effective for the treatment of C. felis, would offer advantages both in practicality of dosing and in cost.
Journal Article
Antitrypanosomal and cytotoxic activities of selected medicinal plants and effect of Cordyline terminalis on trypanosomal nuclear and kinetoplast replication.
TL;DR: From the current study, it can be concluded that the aqueous extract of leaves of C. terminalis shows considerable antitrypanosomal activity and it could be a potential source of new antitry panosomal compounds.
References
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Versão do programa computacional assistat para o sistema operacional windows
TL;DR: It was made a version (Assistat 6.2) of the software for the variance analysis, Assistat, to work in the Windows operating system, since the previous versions were conceived toWork in the DOS operating system DOS (operation system in disk).
Journal ArticleDOI
Enzootiology of Trypanosoma evansi in Pantanal, Brazil
Heitor Miraglia Herrera,Alberto M. R. Dávila,A. Norek,Urbano Gomes Pinto de Abreu,S.S. Souza,Paulo Sérgio D'Andrea,Ana Maria Jansen +6 more
TL;DR: The highest prevalence of T. evansi infection was recorded in horses, although no neurological signs in infected horses were observed, and Diagnosis through standard parasitological tests and IFAT should be used with caution since they may overlook comprovedly infected horses.
Journal ArticleDOI
Pharmacology of diminazene. A review
A.S. Peregrine,M. Mamman +1 more
TL;DR: The current status of knowledge concerning the therapeutic spectrum of Diminazene, resistance to diminazene in trypanosomes, and combination therapeutic regimens in which diminazenes has been administered together with other compounds are considered.