Journal ArticleDOI
Diminazene aceturate in the control of Trypanosoma evansi infection in cats.
A. S. da Silva,Régis Adriel Zanette,Patrícia Wolkmer,Mateus Matiuzzi da Costa,H.A. Garcia,Sonia Terezinha dos Anjos Lopes,Jânio Morais Santúrio,M.M.G. Teixeira,Silvia Gonzalez Monteiro +8 more
TLDR
The therapy used is effective in controlling T. evansi in cats andAlanine aminotransferase, gamma-glutamyltransferase, urea, and creatinine values remained within the normal physiological range in the treated cats.About:
This article is published in Veterinary Parasitology.The article was published on 2009-10-28. It has received 32 citations till now. The article focuses on the topics: Diminazene & Trypanosoma evansi.read more
Citations
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Journal ArticleDOI
Trypanosoma evansi and Surra: A Review and Perspectives on Origin, History, Distribution, Taxonomy, Morphology, Hosts, and Pathogenic Effects
Marc Desquesnes,Philippe Holzmuller,De-Hua Lai,A.P. Dargantes,Zhao-Rong Lun,Sathaporn Jittaplapong +5 more
TL;DR: Surra is a major disease in camels, equines, and dogs, in which it can often be fatal in the absence of treatment, and exhibits nonspecific clinical signs, which are variable from one host and one place to another; however, its immunosuppressive effects interfering with intercurrent diseases or vaccination campaigns might be its most significant and questionable aspect.
Journal ArticleDOI
Pathogenic mechanisms of Trypanosoma evansi infections.
TL;DR: Several attempts have being made to unravel the clinical pathogenic mechanisms in T. evansi infections, yielding various reports which have implicated hemolysis associated to decrease in life span of erythrocytes and extensive erythrophagocytosis being among those that enjoy prominence.
Journal ArticleDOI
Diminazene aceturate—An antiparasitic drug of antiquity: Advances in pharmacology & therapeutics
TL;DR: A systematic review on diminazene aceturate regarding its pharmacological properties suggested promising new applications such as leishmanicidal, amebicidal,anti-pneumocystis, anti-rheumatoid arthritis, antihypertensive agent and mainly as an activator of angiotensin-converting enzyme 2.
Journal ArticleDOI
Trypanocidal activity of the compounds present in Aniba canelilla oil against Trypanosoma evansi and its effects on viability of lymphocytes.
Janice L. Giongo,Rodrigo de Almeida Vaucher,Aleksandro S. Da Silva,Camila B. Oliveira,Cristiane Bastos de Mattos,Matheus D. Baldissera,Michele Rorato Sagrillo,Silvia Gonzalez Monteiro,Dayana L. Custódio,Marcielly Souza de Matos,Paulo de Tarso Barbosa Sampaio,Helder Ferreira Teixeira,Letícia Scherer Koester,Valdir Florêncio da Veiga Junior +13 more
TL;DR: In vitro studies showed that the oil extracted from the stems of A. canelilla may be regarded as a potential natural treatment for trypanosomosis, once proven their in vivo action, may be an interesting alternative in the treatment of infected animals with T. evansi.
Journal ArticleDOI
Tripanossomose em equinos na região sul do Brasil
Aleksandro Schafer da Silva,Olmiro Adair Silveira de Andrade Neto,Márcio Machado Costa,Patrícia Wolkmer,Cinthia Melazzo Mazzantti,Janio Morais Santurio,Sonia Terezinha dos Anjos Lopes,Silvia Gonzalez Monteiro +7 more
TL;DR: The outbreaks of the infection by T. evansi in horses that occurred in southern Brazil were discussed in terms of epidemiology, clinical signs, laboratory tests, pathological findings, diagnosis and treatment by addressing the differences between the cases occurred in the state of Rio Grande do Sul and in other Brazilian states.
References
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Journal ArticleDOI
Is the broad range of hosts and geographical distribution of Trypanosoma evansi attributable to the loss of maxicircle kinetoplast DNA
Z R Lun,S S Desser +1 more
Journal ArticleDOI
Clinical, Parasitological and Immunological Aspects of Experimental Infection with Trypanosoma evansi in Dogs
Lúcia Padilha Cury Thomaz de Aquino,Rosangela Zacarias Machado,Antonio Carlos Alessi,Luiz Carlos Marques,Márcio Botelho de Castro,Euclides Braga Malheiros +5 more
TL;DR: High and persistent antibody levels were detected by both tests and appeared not to correlate with control of parasitaemia.
Journal ArticleDOI
Genetic relatedness among Trypanosoma evansi stocks by random amplification of polymorphic DNA and evaluation of a synapomorphic DNA fragment for species-specific diagnosis.
R M Ventura,G. F. Takeda,R. A. M. S. Silva,Vânia Lúcia Brandão Nunes,Gregory A. Buck,Marta Maria Geraldes Teixeira +5 more
TL;DR: The results showed that this assay may be useful as a diagnostic tool for field-epidemiological studies of T. evansi and disclosed a pattern consisting of a unique synapomorphic DNA fragment (termed Te664) for the T.evansi cluster that was not detected in any other trypanosome species investigated.
Journal ArticleDOI
Chemotherapy of surra in horses and mules with diminazene aceturate
TL;DR: During June-July 2000, an outbreak of surra occurred on an equine breeding farm in Khonkaen Province, Thailand and results revealed that diminazene aceturate appeared to be effective in the first treatment of horses and mules infected with T. evansi.
Journal ArticleDOI
Pathogenesis of Trypanosoma evansi infection in dogs and horses: hematological and clinical aspects
R. A. M. S. Silva,Heitor Miragaia Herrera,Luzimari Borges da Silveira Domingos,Flora Auxiliadora Ximenes,Alberto M. R. Dávila +4 more
TL;DR: Light microscopic studies demonstrated that Trypanosoma evansi produced several alterations in erythrocytes of dogs and horses, which included vacuolation, acanthocytes, dacrocytes, codocytes, microspherocytes and bizarre shapes.