Journal ArticleDOI
(Diphenylphosphino)-biheteroaryls: the first example of a new class of chiral atropisomeric chelating diphosphine ligands for transition metal catalysed stereoselective reactions
Tiziana Benincori,Elisabetta Brenna,Franco Sannicolò,Licia Trimarco,Patrizia Antognazza,Edoardo Cesarotti +5 more
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TLDR
Ruthenium(II) dichloride complexes with (+)- and (−)-2,2′-bis(diphenylphosphino)-4,4′,6,6′-tetramethyl-3,3′-bibenzo[b]thiophene (1a), new chiral atropisomeric heterocyclic ligands, reduce α- and β-oxoesters to α-and β-hydroxyesters with an enantiomeric purity comparable, if not higher, to that reported forAbstract:
Ruthenium(II) dichloride complexes with (+)- and (–)-2,2′-bis(diphenylphosphino)-4,4′,6,6′-tetramethyl-3,3′-bibenzo[b]thiophene (1a), new chiral atropisomeric heterocyclic ligands, reduce α- and β-oxoesters to α- and β-hydroxyesters with an enantiomeric purity comparable, if not higher, to that reported for binap under the same experimental conditions.read more
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New Chiral Phosphorus Ligands for Enantioselective Hydrogenation
Wenjun Tang,Xumu Zhang +1 more
TL;DR: The increasing demand to produce enantiomerically pure pharmaceuticals, agrochemicals, flavors, and other fine chemicals has advanced the field of asymmetric catalytic technologies, and asymmetric hydrogenation utilizing molecular hydrogen to reduce prochiral olefins, ketones, and imines has become one of the most efficient methods for constructing chiral compounds.
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Chiral sulfur ligands for asymmetric catalysis.
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Axially chiral bidentate ligands in asymmetric catalysis
Mary McCarthy,Patrick J. Guiry +1 more
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Recent advances in biaryl-type bisphosphine ligands
TL;DR: Biaryl-type bisphosphine ligands of recent vintage and their effective applications to asymmetric syntheses are reviewed in this paper, where 155 references are provided for bisphphosphines.
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A new class of versatile chiral-bridged atropisomeric diphosphine ligands: remarkably efficient ligand syntheses and their applications in highly enantioselective hydrogenation reactions.
Liqin Qiu,Fuk Yee Kwong,Jing Wu,Wai Har Lam,Shusun Chan,Wing-Yiu Yu,Yue-Ming Li,Rongwei Guo,Zhongyuan Zhou,Albert S. C. Chan +9 more
TL;DR: A series of chiral diphosphine ligands denoted as PQ-Phos was prepared by atropdiastereoselective Ullmann coupling and ring-closure reactions, and the significant ligand dihedral angle effects on the Ir-catalyzed asymmetric hydrogenation of N-heteroaromatic compounds were revealed.
References
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The chemistry of heterocyclic compounds
TL;DR: In this article, it was shown that one of the most common types of known quantities of phenyl phenyl is phenyl oxide (POP) oxide, which is a phenyl-oxyoxy phenyl (PE)-oxyoxyphenyl) that can be obtained from phenyl compounds.
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Asymmetric hydrogenation of .beta.-keto carboxylic esters. A practical, purely chemical access to .beta.-hydroxy esters in high enantiomeric purity
Ryoji Noyori,Takeshi Ohkuma,Masato Kitamura,Hidemasa Takaya,Noboru Sayo,Hidenori Kumobayashi,Susumu Akutagawa +6 more
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Centenary Lecture. Chemical multiplication of chirality: science and applications
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Cationic BINAP-Ru(II) Halide Complexes: Highly Efficient Catalysts for Stereoselective Asymmetric Hydrogenation of .alpha.- and .beta.-Functionalized Ketones
Kazushi Mashima,K. Kusano,Naomasa Sato,Y. Matsumura,Kyoko Nozaki,Hidenori Kumobayashi,Noboru Sayo,Yoji Hori,Takero Ishizaki +8 more
TL;DR: In this paper, a single-crystal X-ray analysis was performed on the Ru(II)-BINAP-Ru (II) complexes and the results showed that the catalytic activities and stereoselectivities depend highly on reaction conditions such as solvent, temperature, and additives.