Journal ArticleDOI
Distribution of nucleotide differences between two randomly chosen cistrons in a subdivided population: the finite island model.
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TLDR
Using the island model of finite size, the distributions as well as the means and variances of dw and db are obtained and it is shown that the actual genic variation in a colony may be much larger than that revealed by the heterozygosity in the colony.About:
This article is published in Theoretical Population Biology.The article was published on 1976-12-01. It has received 46 citations till now. The article focuses on the topics: Population.read more
Citations
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Estimation of levels of gene flow from DNA sequence data.
TL;DR: It is found that in general when there is no recombination, the cladistic method performed better than FST while the reverse was true for rates of recombination similar to those found in eukaryotic nuclear genes, although FST performed better for all recombination rates for very low levels of migration.
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Estimating Divergence Times from Molecular Data on Phylogenetic and Population Genetic Timescales
TL;DR: A review of recent advances in estimating divergence times from molecular data, emphasizing the continuum between processes at the phylogenetic and population genetic scales, and the importance of model testing during the process of divergence time estimation.
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New Statistical Tests of Neutrality for DNA Samples from a Population
TL;DR: Four statistical tests of the neutral model of evolution against a class of alternative models with the common characteristic of having an excess of mutations that occurred a long time ago or a reduction of recent mutations compared to theneutral model are developed.
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Effects of metapopulation processes on measures of genetic diversity.
TL;DR: This work focuses its attention principally on theoretical studies of a classical metapopulation with a 'finite-island' model of population structure, rather than on 'continent- island' models or 'source-sink' models.
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Neutral theory of quantitative genetic variance in an island model with local extinction and colonization.
TL;DR: The results indicate the importance of mutation and migration in maintaining quantitative genetic variance within small local populations, and contrast with Wright's classical conclusion that at least one immigrant per island every other generation is necessary.
References
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On the number of segregating sites in genetical models without recombination.
TL;DR: The distribution is obtained for the number of segregating sites observed in a sample from a population which is subject to recurring, new, mutations but not subject to recombination, and applies approximately to three population models.
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The number of heterozygous nucleotide sites maintained in a finite population due to steady flux of mutations.
TL;DR: The number of heterozygous sites per individual and some related quantities that represent the statistical properties of the mutant frequency distribution are investigated, assuming that a very large number of independent sites are available for mutation.
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Effective number of alleles in a subdivided population
TL;DR: It is shown that the genetic variability in the whole population with stepping stone structure is known if the mutation rate and the variability in a single colony is known, without knowing the migration rate.
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Theoretical foundation of population genetics at the molecular level.
TL;DR: A hypothesis that mutants are selectively neutral at the majority of sites but are selected at a relatively small number of sites was examined, and the roles of associative overdominance and subdivided population structure in maintaining genetic variability were considered.