Open AccessBook
Does stress damage the brain? : understanding trauma-related disorders from a mind-body perspective
TLDR
Can what you see, hear, feel, and experience actually result in a permanent change in your brain? This provocative question arose from research discoveries by J. Douglas Bremner and others that showed that extreme stress might result in lasting damage to the brain this article.Citations
More filters
Book
Does Stress Damage the Brain
TL;DR: The possibility that experiences in the form of traumatic stressors can have long-term effects on the structure and function of the brain is introduced.
Journal ArticleDOI
MRI and PET Study of Deficits in Hippocampal Structure and Function in Women With Childhood Sexual Abuse and Posttraumatic Stress Disorder
J. Douglas Bremner,Meena Vythilingam,Eric Vermetten,Steven M. Southwick,Thomas H. McGlashan,Ahsan Nazeer,Sarfraz Khan,L. Viola Vaccarino,Robert Soufer,Pradeep K. Garg,Chin K. Ng,Lawrence H. Staib,James S. Duncan,Dennis S. Charney +13 more
TL;DR: The results of this study are consistent with deficits in hippocampal function and structure in abuse-related PTSD.
Journal ArticleDOI
Posttraumatic stress disorder: A state-of-the-science review
Charles B. Nemeroff,J. Douglas Bremner,Edna B. Foa,Helen S. Mayberg,Carol S. North,Murray B. Stein +5 more
TL;DR: It would be useful to assess the validity of the PTSD construct, elucidate genetic and experiential contributing factors (and their complex interrelationships), clarify the mechanisms of action for different treatments used in PTSD, discover ways to predict which treatments will be successful for a given individual, develop an operational definition of remission, and explore ways to disseminate effective evidence-based treatments for this condition.
Book ChapterDOI
Structural and functional plasticity of the human brain in posttraumatic stress disorder
TL;DR: Antidepressant treatments and changes in environment can reverse the effects of stress on hippocampal neurogenesis, and humans with PTSD showed increased hippocampal volume with both paroxetine and phenytoin.
Journal ArticleDOI
SEGREGATION AND STRATIFICATION: A Biosocial Perspective
TL;DR: The authors argued that long-term exposure to social disorder and violence because of segregation produces a high allostatic load among African Americans, which leads, in turn, to a variety of deleterious health and cognitive outcomes.