Journal ArticleDOI
Down-/up-conversion luminescence nanocomposites for dual-modal cell imaging
TLDR
The results of cytotoxicity assay and dual-modal luminescence cell imaging application of DC-UC NCs indicate that the as-prepared NCs are biocompatible and applicable in biomedical fields.Abstract:
Dual-modal luminescence nanocomposites (NCs) were successfully prepared via a facile and versatile strategy by embedding the hydrophobic down-conversion (DC) fluorescence ZnS:Mn2+ quantum dots (QDs) and up-conversion (UC) luminescence NaYF4:Er3+/Yb3+ nanoparticles (NPs) into hydrophilic polymer matrixes through in situ cross-linking polymerization. Due to the enriched carboxylic groups in the polymer matrixes, the as-prepared NCs are highly water-stable and bioconjugatable with chemical and biological moieties. The results of cytotoxicity assay and dual-modal luminescence cell imaging application of DC–UC NCs indicate that the as-prepared NCs are biocompatible and applicable in biomedical fields. The current work paves the way to the fabrication of multifunctional NCs including down- and up-conversion dual-modal luminescence, luminescence–magnetism, magnetic targeted drug vehicles and magnetic recyclable catalyst NCs, and will attract wide attention from the fields of chemistry, materials, catalysis, nanotechnology, nanobiotechnology and nanomedicine.read more
Citations
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Journal ArticleDOI
Rhodamine B derivative-functionalized upconversion nanoparticles for FRET-based Fe(3+)-sensing.
TL;DR: A novel fluorescence resonance energy transfer (FRET)-based probe, γ-cyclodextrin modified oleic acid-NaYF4:Yb, Ho upconversion nanoparticles functionalized with a rhodamine B derivative (RBD), has been achieved for Fe(3+)-sensing in aqueous solution with high sensitivity and selectivity.
Monodisperse Upconversion NaYF4 Nanocrystals: Syntheses and Bioapplications
TL;DR: In this paper, nanocrystals were used to create biocompatibility of NaYF4 and LaF3 nano-nocstals in the context of biomedical applications.
Journal ArticleDOI
Simultaneous detection of hydrogen peroxide and glucose in human serum with upconversion luminescence
TL;DR: The results are in good agreement with the clinical data, suggesting that this UCPL nanosensor is highly practical, and the highly sensitive detection of glucose in human sera independent of preconcentration and purification.
Journal ArticleDOI
Magnetic and optical properties of NaGdF4:Nd3+, Yb3+, Tm3+ nanocrystals with upconversion/downconversion luminescence from visible to the near-infrared second window
Xianwen Zhang,Zhi Zhao,Xin Zhang,David B. Cordes,David B. Cordes,Brandon L. Weeks,Bensheng Qiu,Kailasnath Madanan,Kailasnath Madanan,Dhiraj K. Sardar,Jharna Chaudhuri +10 more
TL;DR: In this paper, the authors designed and synthesized NaGdF4:Nd3+, Yb3+, Tm3+ magnetic nanophosphors with combined dual-mode downconversion (DC) and upconversion photoluminescence upon 800 nm excitation.
Journal ArticleDOI
Multifunctional nanomesoporous materials with upconversion (in vivo) and downconversion (in vitro) luminescence imaging based on mesoporous capping UCNPs and linking lanthanide complexes
TL;DR: The doped Gd(3+) ion endows the nanomesoporous materials UCNPs@mSiO2-Ln(dbm)4 with effective T1 signal enhancement, which affords them as potential magnetic resonance imaging (MRI) contrast agents and may provide more exciting opportunities for multimodal bioimaging and multifunctional applications.
References
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Journal ArticleDOI
Semiconductor Nanocrystals as Fluorescent Biological Labels
TL;DR: Semiconductor nanocrystals prepared for use as fluorescent probes in biological staining and diagnostics have a narrow, tunable, symmetric emission spectrum and are photochemically stable.
Journal ArticleDOI
Quantum Dot Bioconjugates for Ultrasensitive Nonisotopic Detection
Warren C. W. Chan,Shuming Nie +1 more
TL;DR: Highly luminescent semiconductor quantum dots (zinc sulfide-capped cadmium selenide) have been covalently coupled to biomolecules for use in ultrasensitive biological detection and these nanometer-sized conjugates are water-soluble and biocompatible.
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In vivo cancer targeting and imaging with semiconductor quantum dots
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Quantum-dot-tagged microbeads for multiplexed optical coding of biomolecules.
TL;DR: Investigation and spectroscopic measurements indicate that the QD-tagged beads are highly uniform and reproducible, yielding bead identification accuracies as high as 99.99% under favorable conditions.
Journal ArticleDOI
Recent advances in the chemistry of lanthanide-doped upconversion nanocrystals
Feng Wang,Xiaogang Liu +1 more
TL;DR: This tutorial review focuses on the recent development of various synthetic approaches and possibilities for chemical tuning of upconversion properties, as well as giving an overview of biological applications of these luminescent nanocrystals.
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