scispace - formally typeset
Journal ArticleDOI

Dulaglutide and cardiovascular outcomes in type 2 diabetes (REWIND): a double-blind, randomised placebo-controlled trial

Rewind Investigators
- 13 Jul 2019 - 
- Vol. 394, Iss: 10193, pp 121-130
Reads0
Chats0
TLDR
Dulaglutide could be considered for the management of glycaemic control in middle-aged and older people with type 2 diabetes with either previous cardiovascular disease or cardiovascular risk factors.
About
This article is published in The Lancet.The article was published on 2019-07-13. It has received 1449 citations till now. The article focuses on the topics: Dulaglutide & Placebo-controlled study.

read more

Citations
More filters
Journal ArticleDOI

A Practical Guide for Cardiologists to the Pharmacological Treatment of Patients with Type 2 Diabetes and Cardiovascular Disease.

TL;DR: Cardiovascular specialists should become familiar with emerging data and be prepared to implement corresponding strategies in their practice to improve the cardiovascular outcomes of their patients.
Journal ArticleDOI

Evaluation of Consistency of Treatment Response Across Regions-the LEADER Trial in Relation to the ICH E17 Guideline.

TL;DR: The global LEADER (NCT01179048) trial as discussed by the authors investigated cardiovascular outcomes of T2D treatment with liraglutide, a glucagon-like peptide-1 receptor agonist.
Journal ArticleDOI

DPP-4 inhibitors and GLP-1RAs: cardiovascular safety and benefits

TL;DR: In this paper , the safety and benefits of incretin-based therapy, a new class of antidiabetic drug, on the health of patient cardiovascular systems were evaluated and a physiological overview was provided.
Journal ArticleDOI

Combined medical strategies for the management of type 2 diabetes mellitus and obesity in adults.

TL;DR: Given the relationship between the pathogenesis of obesity and type 2 diabetes mellitus (T2DM), treatment strategies that can induce weight loss can induce significant health consequences as mentioned in this paper, which can be found in the literature.
References
More filters
Journal ArticleDOI

A more accurate method to estimate glomerular filtration rate from serum creatinine: A new prediction equation

TL;DR: The purpose of this study was to develop an equation from MDRD Study data that could improve the prediction of GFR from serum creatinine concentration, and major clinical decisions in general medicine, geriatrics, and oncology are made by using the Cockcroft-Gault formula and other formulas to predict the level of renal function.
Journal ArticleDOI

A Proportional Hazards Model for the Subdistribution of a Competing Risk

TL;DR: This article proposes methods for combining estimates of the cause-specific hazard functions under the proportional hazards formulation, but these methods do not allow the analyst to directly assess the effect of a covariate on the marginal probability function.

Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33)

TL;DR: The effects of intensive blood-glucose control with either sulphonylurea or insulin and conventional treatment on the risk of microvascular and macrovascular complications in patients with type 2 diabetes in a randomised controlled trial were compared.
Journal ArticleDOI

Using standardized serum creatinine values in the modification of diet in renal disease study equation for estimating glomerular filtration rate.

TL;DR: The MDRD Study equation has now been reexpressed for use with a standardized serum creatinine assay, allowing GFR estimates to be reported in clinical practice by using standardized serumcreatinine and overcoming this limitation to the current use of GFR estimating equations.
Related Papers (5)