Journal ArticleDOI
Effects of combined γ-irradiation and metal (Al+Cd) exposures in Atlantic salmon (Salmo salar L.)
TLDR
The results suggest that the presence of Al+Cd in the water counteracted the gamma-irradiation effect by modifying the transcription of genes encoding proteins involved in the defense mechanisms against free radicals in the cells.About:
This article is published in Journal of Environmental Radioactivity.The article was published on 2010-03-01. It has received 42 citations till now. The article focuses on the topics: Caspase 7 & Protein degradation.read more
Citations
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Journal ArticleDOI
Early stress responses in Atlantic salmon (Salmo salar) exposed to environmentally relevant concentrations of uranium.
You Song,Brit Salbu,Lene Sørlie Heier,Hans-Christian Teien,Ole Christian Lind,Deborah Oughton,Karina Petersen,Bjørn Olav Rosseland,Lindis Skipperud,Knut Erik Tollefsen,Knut Erik Tollefsen +10 more
TL;DR: The results suggest that U may cause oxidative stress in fish liver at concentrations greater than 0.25 mg/L, giving rise to clear induction of several toxicologically relevant biomarker genes, although no significant adverse effects were observed after the relatively short exposure period.
Journal ArticleDOI
A review of multiple stressor studies that include ionising radiation.
TL;DR: Except for one study, none of the studies predicted combined effects following Concentration Addition or Independent Action, and hence, no justified conclusions can be made about synergism or antagonism.
Journal ArticleDOI
External gamma irradiation-induced effects in early-life stages of zebrafish, Danio rerio.
Béatrice Gagnaire,Isabelle Cavalie,Sandrine Pereira,Magali Floriani,Nicolas Dubourg,Virginie Camilleri,Christelle Adam-Guillermin +6 more
TL;DR: The results suggest that gamma irradiation can induce damages on larval neurotransmission, which could have repercussions on locomotion and further characterized further the modes of action of ionizing radiation in fish.
Journal ArticleDOI
Dietary administration of the probiotic SpPdp11: Effects on the intestinal microbiota and immune-related gene expression of farmed Solea senegalensis treated with oxytetracycline.
Silvana Teresa Tapia-Paniagua,S. Vidal,C. Lobo,I. García de la Banda,M.A. Esteban,M.C. Balebona,Miguel Ángel Moriñigo +6 more
TL;DR: The results demonstrated that the richness and diversity of the intestinal microbiota of fish treated with OTC decreased but that these effects were lessened by the simultaneous administration of SpPdp11, and that the joint administration of OTC and S. putrefaciens Pdp11 increases the transcription of genes related to antiapoptotic effects and oxidative stress regulation.
Journal ArticleDOI
Investigating the embryo/larval toxic and genotoxic effects of γ irradiation on zebrafish eggs
TL;DR: The 20-day embryo-larval bioassay showed an enhanced larval resistance to starvation after chronic exposure to γ irradiation and an acceleration in hatching time and possible mechanisms of γ radiotoxicity and implications for radioprotection are discussed.
References
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Journal ArticleDOI
Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes
Jo Vandesompele,Katleen De Preter,Filip Pattyn,Bruce Poppe,Nadine Van Roy,Anne De Paepe,Franki Speleman +6 more
TL;DR: The normalization strategy presented here is a prerequisite for accurate RT-PCR expression profiling, which opens up the possibility of studying the biological relevance of small expression differences.
Journal ArticleDOI
Metals, toxicity and oxidative stress.
TL;DR: This review summarizes recent findings in the metal-induced formation of free radicals and the role of oxidative stress in the carcinogenicity and toxicity of metals.
Journal ArticleDOI
Oxygen free radicals and metallothionein
Masao Sato,Ian Bremner +1 more
TL;DR: The evidence supporting induction of metallothionein synthesis by oxidative stress, possible mediators for this induction, and the radical scavenging capability of met allothioneIn in tissues and cells are reviewed.
Journal ArticleDOI
Toxicology rethinks its central belief
TL;DR: Hormesis demands a reappraisal of the way risks are assessed for the first time in 25 years.
BookDOI
The Toxicology of Fishes
TL;DR: In this paper, the authors present a set of guidelines for the design of fish exposure assessment and modeling in the aquatic environment, including exposure assessment, exposure analysis, and modeling.