Journal ArticleDOI
Effects of pravastatin on lipid levels, in vitro oxidizability of non-HDL lipoproteins and microalbuminuria in IDDM patients'
TLDR
In this paper, the effects of pravastatin on plasma lipid levels, in vitro oxidizability of the non-HDL fraction, metabolic control, urinary albumin excretion, and four serum enzymes (SGPT, SGOT, GT and CPK) were studied in 20 insulin-dependent diabetic patients (IDDM) with incipient nephropathy.About:
This article is published in Diabetes Research and Clinical Practice.The article was published on 1995-09-01. It has received 46 citations till now. The article focuses on the topics: Pravastatin & TBARS.read more
Citations
More filters
Journal ArticleDOI
Effect of lipid reduction on the progression of renal disease: A meta-analysis
Linda F. Fried,Linda F. Fried,Trevor J. Orchard,Trevor J. Orchard,Bertram L. Kasiske,Bertram L. Kasiske +5 more
TL;DR: Lipid reduction may preserve glomerular filtration rate and may decrease proteinuria in patients with renal disease.
Journal ArticleDOI
Statins for Improving Renal Outcomes: A Meta-Analysis
TL;DR: Assessment of the effect of statins on change in kidney function and urinary protein excretion found that statin therapy seems to reduce proteinuria modestly and results in a small reduction in the rate of kidney function loss, especially in populations with cardiovascular disease.
Journal ArticleDOI
Benefits and harms of statin therapy for persons with chronic kidney disease: a systematic review and meta-analysis.
Suetonia C. Palmer,Jonathan C. Craig,Sankar D. Navaneethan,Marcello Tonelli,Fabio Pellegrini,Giovanni F.M. Strippoli +5 more
TL;DR: Statins decrease mortality and cardiovascular events in persons with early stages of CKD, have little or no effect in persons receiving dialysis, and have uncertain effects in kidney transplant recipients.
Journal ArticleDOI
HMG CoA reductase inhibitors (statins) for people with chronic kidney disease not requiring dialysis.
Suetonia C. Palmer,Sankar D. Navaneethan,Jonathan C. Craig,David W. Johnson,Vlado Perkovic,Jörgen Hegbrant,Giovanni F.M. Strippoli +6 more
TL;DR: Potential harms from statin therapy were limited by lack of systematic reporting and were uncertain in analyses that had few events: elevated creatine kinase, elevated liver enzymes, rhabdomyolysis, cancer and withdrawal rates.
Journal ArticleDOI
Meta-analysis: the effect of statins on albuminuria.
TL;DR: This meta-analysis of 15 randomized, placebo-controlled trials found that statins reduced albuminuria and proteinuria and that these effects were small, showed heterogeneous effects, and were often of poor quality.
References
More filters
Journal ArticleDOI
Microalbuminuria Predicts Clinical Proteinuria and Early Mortality in Maturity-Onset Diabetes
TL;DR: It is concluded that microalbuminuria in patients with Type II diabetes is predictive of clinical proteinuria and increased mortality.
Journal ArticleDOI
Microalbuminuria as a predictor of clinical nephropathy in insulin-dependent diabetes mellitus
TL;DR: Elevated levels of microalbuminuria strongly predict the development of clinical diabetic nephropathy, and these levels of AER are potentially reversible, and their detection and treatment may prevent diabetic renal disease.
Journal ArticleDOI
Long-term complications of diabetes mellitus
TL;DR: Retinopathy is so characteristic of diabetes that its presence has been incorporated into the nosologic definition of NIDDM, while lower levels of hyperglycemia that are of sufficient magnitude to be associated with retinopathy are classified as NID DM.
Journal ArticleDOI
Diabetic nephropathy in type 1 (insulin-dependent) diabetes: An epidemiological study
TL;DR: It was concluded that diabetic nephropathy is the major life threatening complication in Type I diabetes of juvenile onset and had a much poorer survival than those without proteinuria; 40 years after onset of diabetes, only 10% of patients who developed nephrophropathy were alive, whereas >70% of Patients who did not develop nephropy survived.