Journal ArticleDOI
Efficient Synthesis, Antibacterial, Antifungal, Antioxidant and Cytotoxicity Study of 2-(2-Hydrazineyl)thiazole Derivatives
Vishnu A. Adole,Rahul A. More,Bapu S. Jagdale,Thansing B. Pawar,Santosh S. Chobe +4 more
- Vol. 5, Iss: 9, pp 2778-2786
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The article was published on 2020-03-06. It has received 44 citations till now. The article focuses on the topics: Thiazole.read more
Citations
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Pyridine- and Thiazole-Based Hydrazides with Promising Anti-inflammatory and Antimicrobial Activities along with Their In Silico Studies.
Vinuta Kamat,Rangappa Santosh,Boja Poojary,Suresh P. Nayak,Banoth Karan Kumar,Murugesan Sankaranarayanan,Faheem,Sheela Khanapure,Delicia A. Barretto,Shyam Kumar Vootla +9 more
TL;DR: Compound 5j emerged as a significant bioactive molecule among the synthesized analogues and showed inhibition in the range of IC50 values—46.29–100.60 μg/mL.
Journal ArticleDOI
Solvent-free grindstone synthesis of four new (E)-7-(arylidene)-indanones and their structural, spectroscopic and quantum chemical study: a comprehensive theoretical and experimental exploration
Vishnu A. Adole,Ravindra Haribhau Waghchaure,Sandip S. Pathade,Manohar R. Patil,Thansing B. Pawar,Bapu S. Jagdale +5 more
TL;DR: In this paper, four new compounds of (E)-7-(arylidene)-indanone skeleton have been synthesized using a grindstone chemistry approach; environmentally viable protocol.
Journal ArticleDOI
Thiazole–Chalcone Hybrids as Prospective Antitubercular and Antiproliferative Agents: Design, Synthesis, Biological, Molecular Docking Studies and In Silico ADME Evaluation
TL;DR: In this paper, a series of thiazole and chalcone pharmacophores were designed, synthesized and characterized and further evaluated for antitubercular and antiproliferative activities by employing standard protocols.
Journal ArticleDOI
DFT computational insights into structural, electronic and spectroscopic parameters of 2-(2-Hydrazineyl)thiazole derivatives: a concise theoretical and experimental approach
TL;DR: It has been uncovered that compounds containing thiazole moiety display noteworthy biological properties, which have attracted the attention of many researchers in chemical biology as well as in me... as discussed by the authors.
Journal ArticleDOI
Synthesis, anti-proliferative activity, gene expression, docking and DFT investigation of novel Pyrazol-1-yl-thiazol-4(5H)-one derivatives
TL;DR: In this paper, the novel thaizolone derivatives 8a-n were synthesized via the reaction between thioamide derivatives 4a, b with chloroacetic acid and the appropriate aldehyde derivatives 7a-g in acetic acid.
References
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Paul T. Anastas,Nicolas Eghbali +1 more
TL;DR: The concepts of design and the scientific philosophy of Green Chemistry are covered with a set of illustrative examples and the challenge of using the Principles as a cohesive design system is discussed.
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Resazurin microtiter assay plate: Simple and inexpensive method for detection of drug resistance in Mycobacterium tuberculosis
Juan Carlos Palomino,Anandi Martin,Mirtha Camacho,Humberto Guerra,Jean Swings,Françoise Portaels +5 more
TL;DR: This method for detecting multidrug-resistant Mycobacterium tuberculosis by using a reduction of resazurin is simple, inexpensive, and rapid and might be used with other antituberculosis drugs.
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Polyethylene glycol and solutions of polyethylene glycol as green reaction media
TL;DR: Aqueous biphasic reactive extraction (ABRE) can successfully integrate the solvent properties of polyethylene glycol (PEG) and its phase-transfer characteristics into a single efficient system which can additionally be manipulated to facilitate the separation of reactants and/or catalysts from products.
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The Green ChemisTREE: 20 years after taking root with the 12 principles
Hanno C. Erythropel,Julie B. Zimmerman,Tamara M. de Winter,Laurène Petitjean,Fjodor Melnikov,Chun Ho Lam,A.W. Lounsbury,Karolina E. Mellor,Nina Z. Janković,Qingshi Tu,Lauren N. Pincus,Mark M. Falinski,Wenbo Shi,Philip Coish,Desiree L. Plata,Paul T. Anastas +15 more
TL;DR: The Green ChemisTrees as discussed by the authors is a showcase for the diversity of research and achievements stemming from green chemistry, inspired by tree diagrams that illustrate diversity of products stemming from raw materials.
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Neurochemical properties of ramelteon (TAK-375), a selective MT1/MT2 receptor agonist.
Koki Kato,Keisuke Hirai,Keiji Nishiyama,Osamu Uchikawa,Kohji Fukatsu,Shigenori Ohkawa,Yuji Kawamata,Shuji Hinuma,Masaomi Miyamoto +8 more
TL;DR: Results indicate that ramelteon is a potent and highly selective agonist of MT1/MT2 melatonin receptors and inhibited forskolin-stimulated cAMP production in the CHO cells that express the human MT1 or MT2 receptors.