Journal ArticleDOI
Efficient Synthesis of Fine Chemicals and Organic Building Blocks Applying Palladium‐Catalyzed Coupling Reactions
TLDR
In this article, the importance of selected palladium-catalyzed coupling reactions for fine chemical synthesis is shown, and a focus is made on the refinement of aryl halides.Abstract:
The importance of selected palladium-catalyzed coupling reactions for fine chemical synthesis is shown. Special focus is made on the refinement of aryl halides. Apart from known industrial processes the potential use of recently developed palladium catalysts from our group is demonstrated.read more
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Journal ArticleDOI
Iron-Catalyzed Reactions in Organic Synthesis
TL;DR: A new iron(III) halide-promoted aza-Prins cyclization between γ,δ-unsaturated tosylamines and aldehydes provides six-membered azacycles in good to excellent yields.
Journal ArticleDOI
Large-scale applications of transition metal-catalyzed couplings for the synthesis of pharmaceuticals.
Javier Magano,Joshua R. Dunetz +1 more
Journal ArticleDOI
Iron-Catalyzed Cross-Coupling Reactions
TL;DR: The method allows for consecutive cross-coupling processes in one pot, as exemplified by the efficient preparation of compound 12, and has been applied to the first synthesis of the cytotoxic marine natural product montipyridine 8.
Journal ArticleDOI
High‐Turnover Palladium Catalysts in Cross‐Coupling and Heck Chemistry: A Critical Overview
TL;DR: In this article, the problems associated with developing high-turnover catalysts for the cross-coupling and Heck reactions are discussed, and a review of new developments in the area, principally constituted by palladacycles and coordinatively unsaturated Pd catalysts featuring bulky phosphanes of high donicity, are reviewed from a mechanistic and synthetic standpoint.
Journal ArticleDOI
Preparation, Structure, and Reactivity of Nonstabilized Organoiron Compounds. Implications for Iron-Catalyzed Cross Coupling Reactions
TL;DR: It is shown that nucleophiles unable to undergo beta-hydride elimination, such as MeLi, PhLi, or PhMgBr, rapidly reduce Fe(3+) to Fe(2+) and then exhaustively alkylate the metal center.
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