Journal ArticleDOI
Efficient water soluble O-carboxymethyl chitosan nanocarrier for the delivery of curcumin to cancer cells
A. Anitha,S. Maya,N. Deepa,Krishna Prasad Chennazhi,Shantikumar V. Nair,Hiroshi Tamura,Rangasamy Jayakumar +6 more
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TLDR
Cytotoxicity studies by MTT assay indicated that curcumin-O-CMC Nps were toxic to cancer and non-toxic to normal cells and indicated O-C MC as a promising nanomatrix for drug delivery applications.About:
This article is published in Carbohydrate Polymers.The article was published on 2011-01-10. It has received 309 citations till now. The article focuses on the topics: Drug carrier & Drug delivery.read more
Citations
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Development of zein nanoparticles coated with carboxymethyl chitosan for encapsulation and controlled release of vitamin D3.
Yangchao Luo,Zi Teng,Qin Wang +2 more
TL;DR: Encapsulation of hydrophobic nutrients in zein nanoparticles with CMCS coatings is a promising approach to enhance chemical stability and controlled release property and Photostability against UV light was significantly improved.
Journal ArticleDOI
Preparation, characterization, in vitro drug release and biological studies of curcumin loaded dextran sulphate–chitosan nanoparticles
A. Anitha,V. G. Deepagan,V.V. Divya Rani,Deepthy Menon,Shantikumar V. Nair,Rangasamy Jayakumar +5 more
TL;DR: The results showed preferential killing of cancer cells compared to normal cells by the curcumin-loaded nanoparticles, which could be a promising candidate in cancer therapy.
Journal ArticleDOI
Impact of chitosan composites and chitosan nanoparticle composites on various drug delivery systems: A review.
M. Abd Elgadir,Md. Salim Uddin,Sahena Ferdosh,Aishah Adam,Ahmed Jalal Khan Chowdhury,Md. Zaidul Islam Sarker +5 more
TL;DR: The physicochemical and drug delivery properties of chitosan are summarized, selected studies on utilization of ch itosan and chitOSan-based nanoparticle composites in various drug delivery systems are selected, andselected studies on the application of chITosan films in both drug delivery and wound healing are selected.
Journal ArticleDOI
Carboxymethyl chitosan: Properties and biomedical applications.
TL;DR: The most recent applications of CMC derivatives with antimicrobial, anticancer, antitumor, antioxidant and antifungal biological activities in various areas like wound healing, tissue engineering, drug/enzyme delivery, bioimaging and cosmetics are highlighted.
Journal ArticleDOI
Biomedical applications of carboxymethyl chitosans.
TL;DR: This review will focus on preparative methods and physicochemical and biological properties of carboxymethyl chitosan with particular emphasis on biomedical and pharmaceutical applications of this derivative of chitOSan.
References
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Chitosan as Antimicrobial Agent: Applications and Mode of Action
TL;DR: The current review of 129 references describes the biological activity of several chitosan derivatives and the modes of action that have been postulated in the literature.
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Therapeutic Nanoparticles for Drug Delivery in Cancer
TL;DR: In this paper, the authors proposed a passive targeting mechanism, active targeting strategies using ligands or antibodies directed against selected tumor targets amplify the specificity of these therapeutic nanoparticles, enabling them to carry their loaded active drugs to cancer cells by selectively using the unique pathophysiology of tumors.
Journal Article
Therapeutic Nanoparticles for Drug Delivery in Cancer
TL;DR: Multifunctional and multiplex nanoparticles are now being actively investigated and are on the horizon as the next generation of nanoparticles, facilitating personalized and tailored cancer treatment.
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Implantable applications of chitin and chitosan
Eugene Khor,Lee Yong Lim +1 more
TL;DR: This review surveys select works of key groups in Asia developing chitin and chitosan materials for implantable biomedical applications and finds Japan has been the undisputed leader, but other Asian nations, namely Korea, Singapore, Taiwan and Thailand have also made notable contributions.
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Stability of curcumin in buffer solutions and characterization of its degradation products
Ying-Jan Wang,Min-Hsiung Pan,Ann-Lii Cheng,Liang-In Lin,Yuan Soon Ho,Chang-Yao Hsieh,Jen-Kun Lin +6 more
TL;DR: It was shown that decomposition was pH-dependent and occurred faster at neutral-basic conditions and vanillin, ferulic acid, feruloyl methane were identified as minor degradation products and the amount of vanillin increased with incubation time.
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