Journal ArticleDOI
Electrochemical biosensors for DNA hybridization and DNA damage
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TLDR
Using the peptide nucleic acid in the biosensor recognition layer greatly increased the specificity of the DNA hybridization biosensor making it possible to detect point mutations (single-base mismatches) in DNA.About:
This article is published in Biosensors and Bioelectronics.The article was published on 1998-09-01. It has received 276 citations till now. The article focuses on the topics: DNA damage & Nucleic acid thermodynamics.read more
Citations
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Journal ArticleDOI
DNA biosensors and microarrays.
TL;DR: This exhibition celebrates the centenary of the establishment of the University of Lyon with a celebration of the 100th anniversary of the birth of Jean-Bertrand Aristide Dejerine.
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From DNA biosensors to gene chips.
TL;DR: The preparation, operation and applications of biosensors and gene chips, which provide fast, sensitive and selective detection of DNA hybridization, are described.
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Electrochemistry of nucleic acids.
Emil Paleček,Martin Bartošík +1 more
TL;DR: Oscillographic polarography, at controlled alternating current, was used in the electrochemical analysis of nucleic acids and briefly summarizes some properties of the elimination voltammetry with linear scan (EVLS) method.
Journal ArticleDOI
Electrochemical genosensor design: immobilisation of oligonucleotides onto transducer surfaces and detection methods
TL;DR: The present report reviews immobilisation techniques of purified oligonucleotides on electrochemical transducers and their corresponding detection techniques and special attention is given to hybridisation biosensing based on electroactive indicators.
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Materials and techniques for electrochemical biosensor design and construction
S.F Zhang,G Wright,Ying Yang +2 more
TL;DR: This review aims to highlight recent developments in materials and techniques for electrochemical biosensor design and construction, raising hopes that the problems related to interactions between foreign surfaces and biological fluids and tissues may soon be solved.
References
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Book
Nucleic Acids in Chemistry and Biology
TL;DR: This book discusses the development of Nucleic Acids Research, the role of RNA Structural Motifs, and other topics related to RNA Structure and Function in Viral Systems.
Journal Article
Structural aspects of the p53 protein in relation to gene evolution.
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Peptide Nucleic Acid Probes for Sequence-Specific DNA Biosensors
Joseph Wang,Emil Paleček,Peter E. Nielsen,Gustavo A. Rivas,Xiaohua Cai,Haruki Shiraishi,Narasaiah Dontha,and Denbai Luo,Percio A. M. Farias +8 more
TL;DR: PNA recognition layers thus offer significant advantages for sequence-specific DNA biosensors, compared to their DNA counterparts, including significantly higher sensitivity and specificity, faster hybridization at room and elevated temperatures, minimal dependence on ionic strength, and use of shorter probes.
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From polarography of DNA to microanalysis with nucleic acid-modified electrodes
TL;DR: Past, present and future aspects of nucleic acid voltammetric analysis are reviewed.
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Oscillographic polarography of highly polymerized deoxyribonucleic acid.
TL;DR: It is shown that nucleotides, nucleosides and the bases of nucleic acids can be analysed by alternating current oscillographic polarography and polymerized deoxyribonucleic acid was studied by this method.