Journal ArticleDOI
Enhanced camptothecin production by ethanol addition in the suspension culture of the endophyte, Fusarium solani
TLDR
The study indicates a dual role of ethanol, presumably as an elicitor and also as a carbon/energy source, leading to enhanced biomass and camptothecin production.About:
This article is published in Bioresource Technology.The article was published on 2015-07-01. It has received 48 citations till now. The article focuses on the topics: Fusarium solani & Energy source.read more
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Book ChapterDOI
Endophytic Fungi As the Alternate Source of High-Value Plant Secondary Metabolites
TL;DR: Various methods used to optimize the culture conditions, including one strain many compounds (OSMAC), response surface method (RSM), and the genetic tools along with other techniques like cocultivation and epigenetic modification to overcome the problem of attenuation of metabolite synthesis, are discussed.
Book ChapterDOI
Frontiers in Fungal Endophytes Associated with Medicinal Orchids
TL;DR: In this paper , the authors have explored the group of fungal endophytes associated with medicinal orchids and found that these associations give insights of the host-microbe interaction to understand the ideal production of new and important fungal metabolites for sustainable development of bioproducts.
References
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Journal ArticleDOI
Nucleic acid-based approaches to investigate microbial-related cheese quality defects
Daniel J. O'Sullivan,Linda Giblin,Paul L.H. McSweeney,Jeremiah J. Sheehan,Paul D. Cotter,Paul D. Cotter +5 more
TL;DR: The DNA-based methods that are available to detect/quantify spoilage bacteria, and relevant metabolic pathways in cheeses are reviewed and it is highlighted how these strategies can be employed to improve cheese quality and reduce the associated economic burden on cheese processors.
Journal ArticleDOI
The Catharanthus alkaloids: pharmacognosy and biotechnology.
TL;DR: Despite the availability of only a limited number of biosynthetic genes, the research on C. roseus has already led to a broad scientific spin-off and it is clear that many interesting results can be expected when more genes become available.
Journal ArticleDOI
An endophytic fungus from Nothapodytes foetida that produces camptothecin.
TL;DR: Isolation of an organism producing camptothecin and its fermentation may, in the future, provide an easily accessible source for the production of this anticancer drug precursor molecule.
Journal ArticleDOI
An endophytic fungus from Camptotheca acuminata that produces camptothecin and analogues
TL;DR: The results offer a caution as to the possibility of using endophytic fungi as alternate sources of plant secondary metabolite production, and further studies have been initiated on the analysis of the upstream metabolic intermediates to understand the steps at which the production of the metabolites in question is constrained.
Journal ArticleDOI
Endophytic fungal strains of Fusarium solani, from Apodytes dimidiata E. Mey. ex Arn (Icacinaceae) produce camptothecin, 10-hydroxycamptothecin and 9-methoxycamptothecin
S. Shweta,Sebastian Zuehlke,B. T. Ramesha,V. Priti,P. Mohana Kumar,Gudasalamani Ravikanth,Michael Spiteller,Ramesh Vasudeva,R. Uma Shaanker +8 more
TL;DR: Endophytic fungi strains from Apodytes dimidiata (Icacinaceae), a medium sized tree from the Western Ghats, India are isolated and identified as Fusarium solani using both ITS rDNA sequencing and spore morphology, both of which produced camptothecin and 9-methoxycamPTothecin in their mycelia.