Journal ArticleDOI
Enhanced camptothecin production by ethanol addition in the suspension culture of the endophyte, Fusarium solani
TLDR
The study indicates a dual role of ethanol, presumably as an elicitor and also as a carbon/energy source, leading to enhanced biomass and camptothecin production.About:
This article is published in Bioresource Technology.The article was published on 2015-07-01. It has received 48 citations till now. The article focuses on the topics: Fusarium solani & Energy source.read more
Citations
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In vitro elicitation of Camptothecin by challenging with biotic elicitors in Nothapodytes nimmoniana (J.Graham) Mabb
TL;DR: In this article , Nothapodytes nimmoniana (J. Graham) Mabb. (Olacaceae), a plant native to India's Western Ghats, has been harnessed for the production of CPT.
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Growth promotion mediated by endophytic fungi in cloned seedlings of Eucalyptus grandis x Eucalyptus urophylla hybrids
Luciana Cristina Vitorino,Layara Alexandre Bessa,Ligia Guimarães Carvalho,Fabiano Guimarães Silva +3 more
TL;DR: Eucalyptus cultivation has expanded considerably in Brazilian systems, leading to the current search for technologies to optimize growing conditions and the production of seedlings in nurseries, where cloned seedlings inoculated with Trichoderma sp.
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Endophytic fungus Diaporthe caatingaensis MT192326 from Buchanania axillaris: An indicator to produce biocontrol agents in plant protection.
Madhankumar Dhakshinamoorthy,Kannan Kilavan Packiam,Ponnusamy Senthil Kumar,Tamilselvi Saravanakumar +3 more
TL;DR: In this article, the authors have focused on the isolation, screening and evaluation of Camptothecin (CPT) and its derivatives, an anticancer molecule from endophytic fungus Diaporthe caatingaensis MT192326 of the medicinal plant, Buchanania axillaris.
Journal ArticleDOI
Production of naphthoquinones and phenolics by a novel isolate Fusarium solani PSC-R of Palk Bay and their industrial applications
Janarthanam Rathna,Kumanan Bharathi Yazhini,Antony Alex Kennedy Ajilda,Halliah Gurumallesh Prabu,Shunmugiah Karutha Pandian +4 more
TL;DR: The obtained results document the effective means of enhanced production of naphthoquinones and phenolics in the suspension culture of F. solani PSC-R at bioreactor level.
Journal ArticleDOI
Production, Bioprocessing and Anti-Proliferative Activity of Camptothecin from Penicillium chrysogenum, “An Endozoic of Marine Sponge, Cliona sp.”, as a Metabolically Stable Camptothecin Producing Isolate
Ashraf S.A. El-Sayed,Wafaa H.B. Hassan,Sherouk Hussein Sweilam,Mohammed H. Alqarni,Zeinab I El Sayed,M. M. Abdel-Aal,Eman M. Nagiub Abdelsalam,Sahar Abdelaziz +7 more
TL;DR: This is the first report describing the feasibility of P. chrysogenum, endozoic of Cliona sp.
References
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Journal ArticleDOI
Nucleic acid-based approaches to investigate microbial-related cheese quality defects
Daniel J. O'Sullivan,Linda Giblin,Paul L.H. McSweeney,Jeremiah J. Sheehan,Paul D. Cotter,Paul D. Cotter +5 more
TL;DR: The DNA-based methods that are available to detect/quantify spoilage bacteria, and relevant metabolic pathways in cheeses are reviewed and it is highlighted how these strategies can be employed to improve cheese quality and reduce the associated economic burden on cheese processors.
Journal ArticleDOI
The Catharanthus alkaloids: pharmacognosy and biotechnology.
TL;DR: Despite the availability of only a limited number of biosynthetic genes, the research on C. roseus has already led to a broad scientific spin-off and it is clear that many interesting results can be expected when more genes become available.
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An endophytic fungus from Nothapodytes foetida that produces camptothecin.
TL;DR: Isolation of an organism producing camptothecin and its fermentation may, in the future, provide an easily accessible source for the production of this anticancer drug precursor molecule.
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An endophytic fungus from Camptotheca acuminata that produces camptothecin and analogues
TL;DR: The results offer a caution as to the possibility of using endophytic fungi as alternate sources of plant secondary metabolite production, and further studies have been initiated on the analysis of the upstream metabolic intermediates to understand the steps at which the production of the metabolites in question is constrained.
Journal ArticleDOI
Endophytic fungal strains of Fusarium solani, from Apodytes dimidiata E. Mey. ex Arn (Icacinaceae) produce camptothecin, 10-hydroxycamptothecin and 9-methoxycamptothecin
S. Shweta,Sebastian Zuehlke,B. T. Ramesha,V. Priti,P. Mohana Kumar,Gudasalamani Ravikanth,Michael Spiteller,Ramesh Vasudeva,R. Uma Shaanker +8 more
TL;DR: Endophytic fungi strains from Apodytes dimidiata (Icacinaceae), a medium sized tree from the Western Ghats, India are isolated and identified as Fusarium solani using both ITS rDNA sequencing and spore morphology, both of which produced camptothecin and 9-methoxycamPTothecin in their mycelia.