Epidemiology of adolescent idiopathic scoliosis
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TLDR
For example, this paper found that the prevalence of curves with higher Cobb angles is substantially higher in girls than in boys, and the female to male ratio rises from 1.5:1 to 3:1 and increases substantially with increasing age.Abstract:
Adolescent idiopathic scoliosis is a common disease with an overall prevalence of 0.47–5.2 % in the current literature. The female to male ratio ranges from 1.5:1 to 3:1 and increases substantially with increasing age. In particular, the prevalence of curves with higher Cobb angles is substantially higher in girls than in boys: The female to male ratio rises from 1.4:1 in curves from 10° to 20° up to 7.2:1 in curves >40°. Curve pattern and prevalence of scoliosis is not only influenced by gender, but also by genetic factors and age of onset. These data obtained from school screening programs have to be interpreted with caution, since methods and cohorts of the different studies are not comparable as age groups of the cohorts and diagnostic criteria differ substantially. We do need data from studies with clear standards of diagnostic criteria and study protocols that are comparable to each other.read more
Citations
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Journal ArticleDOI
Scoliosis and Pectus Excavatum in Adolescents: Does the Nuss Procedure Affect the Scoliotic Curvature?
Marco Ghionzoli,Alessandra Martin,Martina Bongini,Ubaldo Bongini,Gastone Ciuti,Laura Grisotto,V. Monaco,Arianna Menciassi,Claudio Defilippi,Antonio Messineo +9 more
TL;DR: It seems that MIRPE should be offered during puberty as a timely option for treating PE and stabilizing mild/moderate scoliosis progression, when concurrent.
Journal ArticleDOI
Association Between Vertebral Cross‐sectional Area and Vertebral Wedging in Children and Adolescents: A Cross‐sectional Analysis
TL;DR: The hypothesis that smaller vertebral CSA is associated with greater vertebral deformity during growth, as in adulthood is supported, and cross‐sectional results support the hypothesis.
Journal ArticleDOI
Treatment of adolescent idiopathic scoliosis and evaluation of the adolescent patient
John J. Kelly,Neil V. Shah,Taylor J. Freetly,Joanne C. Dekis,Omar K. Hariri,Sarah E. Walker,Jenna Borrelli,Nicholas H. Post,Bassel G. Diebo,William P. Urban,Carl B. Paulino +10 more
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A QTL for conformation of back and croup influences lateral gait quality in Icelandic horses
Maria K. Rosengren,Heiðrún Sigurðardóttir,Heiðrún Sigurðardóttir,Susanne Eriksson,Rakan Naboulsi,Ahmad Jouni,Miguel Novoa-Bravo,Elsa Albertsdóttir,Þorvaldur Kristjánsson,Marie Rhodin,Åsa Viklund,Brandon D. Velie,Juan J. Negro,Marina Solé,Gabriella Lindgren,Gabriella Lindgren +15 more
TL;DR: In this article, the authors identify genomic regions associated with conformation of back and croup in Icelandic horses and investigate their effects on riding ability using a genome-wide association analysis using the 670 K+ Axiom Equine Genotyping Array.
Journal ArticleDOI
A novel classification method for mild adolescent idiopathic scoliosis using 3D ultrasound imaging
D. Yang,T.T.Y. Lee,K.K.L. Lai,Y.S. Wong,L.N. Wong,J.L. Yang,T.P. Lam,René M. Castelein,J.C.Y. Cheng,Yongping Zheng +9 more
TL;DR: The study demonstrated the possibility of a 3D ultrasound-based method for mild AIS curve classification and measured Cobbs and denoted major curve as ground truth to indicate the presence of a possible structural curve.
References
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Alagille syndrome is caused by mutations in human Jagged1, which encodes a ligand for Notch1
Linheng Li,Ian D. Krantz,Yu Deng,Yu Deng,Anna Genin,Amy B. Banta,Colin Collins,Ming Qi,Barbara J. Trask,Wen Lin Kuo,Joanne Cochran,Teresa Costa,Mary Ella M Pierpont,Elizabeth B. Rand,David A. Piccoli,Leroy Hood,Nancy B. Spinner +16 more
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Journal ArticleDOI
Mutations in the human Jagged1 gene are responsible for Alagille syndrome
Takaya Oda,Abdel G. Elkahloun,Brian L. Pike,Kazuki Okajima,Ian D. Krantz,Anna Genin,David A. Piccoli,Paul S. Meltzer,Nancy B. Spinner,Francis S. Collins,Settara C. Chandrasekharappa +10 more
TL;DR: It is concluded that AGS is caused by haploinsufficiency of JAG1, the human homologue of rat Jagged1, which encodes a ligand for the Notch receptor, an attractive candidate gene for a developmental disorder in humans.
Journal ArticleDOI
Adolescent idiopathic scoliosis.
TL;DR: Adolescent idiopathic scoliosis affects 1-3% of children in the at-risk population of those aged 10-16 years and the aetiopathogensis of this disorder remains unknown, with misinformation about its natural history.
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Adult scoliosis: prevalence, SF-36, and nutritional parameters in an elderly volunteer population
Frank J. Schwab,Ashok Dubey,Lorenzo Gamez,Abdelkrim Benchikh El Fegoun,Ki Hwang,Murali Pagala,J.-P. Farcy +6 more
TL;DR: The scoliosis prevalence rate of 68% found in this study reveals a rate significantly higher than reported in other studies, and appears to reflect the targeted selection of an elderly group.
Journal ArticleDOI
Adolescent idiopathic scoliosis.
TL;DR: Adolescent idiopathic scoliosis is a common problem; its prevalence in the general population is about 1.8 percent, if minor curvatures of 5 to 10 degrees are included.
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