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Epidemiology of adolescent idiopathic scoliosis

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TLDR
For example, this paper found that the prevalence of curves with higher Cobb angles is substantially higher in girls than in boys, and the female to male ratio rises from 1.5:1 to 3:1 and increases substantially with increasing age.
Abstract
Adolescent idiopathic scoliosis is a common disease with an overall prevalence of 0.47–5.2 % in the current literature. The female to male ratio ranges from 1.5:1 to 3:1 and increases substantially with increasing age. In particular, the prevalence of curves with higher Cobb angles is substantially higher in girls than in boys: The female to male ratio rises from 1.4:1 in curves from 10° to 20° up to 7.2:1 in curves >40°. Curve pattern and prevalence of scoliosis is not only influenced by gender, but also by genetic factors and age of onset. These data obtained from school screening programs have to be interpreted with caution, since methods and cohorts of the different studies are not comparable as age groups of the cohorts and diagnostic criteria differ substantially. We do need data from studies with clear standards of diagnostic criteria and study protocols that are comparable to each other.

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Journal ArticleDOI

Whole-Exome Sequencing Identifies Genetic Variants for Severe Adolescent Idiopathic Scoliosis in a Taiwanese Population

TL;DR: Wang et al. as discussed by the authors performed whole-exome sequencing on 11 unrelated Taiwanese patients with a Cobb's angle greater than 40 degrees and identified more than 200 potential pathogenic rare variants, however, most of which were carried only by one individual.
Journal ArticleDOI

Application of the Schroth Method in the Treatment of Idiopathic Scoliosis: A Systematic Review and Meta-Analysis

TL;DR: In this paper , the effect size of the Schroth exercise ranged from almost moderate to large, for the outcomes used: Cobb angle (ES = −0.492, p ˂ 0.005); ATR (Es = − 0.471, p = 0.013); QoL (ES= 1.087, p  0.001).
Proceedings ArticleDOI

Analysis of research results of physical development in children aged 5-6 years in Stara Zagora Municipality - Bulgaria

TL;DR: The high incidence of disturbed posture among preschool children is not only a public concern but also a public health problem for wider preventive measures to improve the motor activity of children and it is necessary to draw up large-scale national programs for early diagnosis and prevention of vertebral distortions at pre-school and school age.
Journal Article

Do Pediatric Hospitals Improve Operative Efficiency?

TL;DR: A retrospective review of pediatric patients undergoing posterior spinal fusion (PSF) was performed as discussed by the authors , where the procedures were performed at a general hospital (GH) the first two years, and at a pediatric hospital (PH) the subsequent years.
References
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Journal ArticleDOI

Mutations in the human Jagged1 gene are responsible for Alagille syndrome

TL;DR: It is concluded that AGS is caused by haploinsufficiency of JAG1, the human homologue of rat Jagged1, which encodes a ligand for the Notch receptor, an attractive candidate gene for a developmental disorder in humans.
Journal ArticleDOI

Adolescent idiopathic scoliosis.

TL;DR: Adolescent idiopathic scoliosis affects 1-3% of children in the at-risk population of those aged 10-16 years and the aetiopathogensis of this disorder remains unknown, with misinformation about its natural history.
Journal ArticleDOI

Adult scoliosis: prevalence, SF-36, and nutritional parameters in an elderly volunteer population

TL;DR: The scoliosis prevalence rate of 68% found in this study reveals a rate significantly higher than reported in other studies, and appears to reflect the targeted selection of an elderly group.
Journal ArticleDOI

Adolescent idiopathic scoliosis.

TL;DR: Adolescent idiopathic scoliosis is a common problem; its prevalence in the general population is about 1.8 percent, if minor curvatures of 5 to 10 degrees are included.
Related Papers (5)
Trending Questions (1)
Why does scoliosis affect more women than men?

Scoliosis affects more women than men, with a female to male ratio ranging from 1.5:1 to 3:1, and increasing with age.