Open AccessJournal Article
Evaluation of hepatoprotective activity of vernonia cinerea (l.) less and cuminum cyminum in carbon tetrachloride induced liver damage in rats
TLDR
Herbal powder reversed the deleterious effects of CCl4 and the enzymes were found to be near normal, demonstrating the protective nature of herbal powder against CCl 4 induced liver damage.Abstract:
The present study deals with the effect of herbal powder of Vernonia cinerea and Cuminum cyminum on tissue defense system against CCl4 (carbon tetrachloride) induced hepatic injury in rats. CCl4 diluted with liquid paraffin oil (1:1 ratio) in a dose of 1ml / kg body wt was given intraperitoneally for 2 days. Herbal powder as a suspension of water (10mg / 100g body wt / day) was administered orally for 15 days to rats intoxicated with CCl4. Induction with CCl4 resulted in an increase in the levels of aspartate transaminases, alkaline phosphatase, alanine transaminases and total bilirubin in serum. Post treatment with herbal powder reversed the deleterious effects of CCl4 and the enzymes were found to be near normal. These findings demonstrate the protective nature of herbal powder against CCl4 induced liver damage.read more
Citations
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Journal ArticleDOI
A review on ethno-medicinal uses and pharmacology of Vernonia cinerea Less.
Nittya K Dogra,Suresh Kumar +1 more
TL;DR: The plant has been evaluated for varied pharmacological activities to validate its traditional claims, and has been scientifically reported to possess anti-inflammatory, antidiabetic, renoprotective, anticancer, antiviral, antimicrobial activities, etc.
Journal Article
Hepatoprotective effects of brown algae padina tetrastromatica against carbon tetrachloride induced hepatoxicity
TL;DR: The main objective of as discussed by the authors was to investigate the antioxidant and hepatoprotective effects of brown algae Padina tetrastromatica against carbon tetrachloride using animal model mice.
Journal ArticleDOI
Hepatoprotective plants role in human health: A cross-kingdom review
Harsha Motwani,Harshida Gadhavi,Naman Mangukia,Saumya K. Patel,Rakesh Rawal,Hitesh A Solanki +5 more
TL;DR: The present review is aimed to compile the available data of promising hepatoprotective plants and introduce the cross-kingdom gene regulation approach as potential therapy for human health care.
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Journal ArticleDOI
Mechanisms of carbon tetrachloride toxicity
TL;DR: Le CCl 4 provoque une degenerescence lipidique et une necrose centrolobulaire du foie dans la peroxydation lipidique and les troubles hepatocellulaires de l'homeostase du calcium.
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