Journal ArticleDOI
Extracellular microelectrode sampling bias.
A.L. Towe,G.W. Harding +1 more
TLDR
The effect of electrode sampling bias to be significant was shown and it was shown that the probability of a successful isolation is largely a function of the cross-sectional area of the axon.About:
This article is published in Experimental Neurology.The article was published on 1970-11-01. It has received 148 citations till now. The article focuses on the topics: Antidromic.read more
Citations
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Journal ArticleDOI
What we can do and what we cannot do with fMRI
TL;DR: An overview of the current state of fMRI is given, and the current understanding of the haemodynamic signals and the constraints they impose on neuroimaging data interpretation are presented.
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Interpreting the BOLD signal.
TL;DR: The current understanding of the causal relationships between neural activity and the blood-oxygen-level-dependent (BOLD) signal is described, and how these analyses have challenged some basic assumptions that have guided neuroscience are reviewed.
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The underpinnings of the BOLD functional magnetic resonance imaging signal.
TL;DR: The good coverage and high resolution afforded by functional magnetic resonance imaging make it an excellent tool for the noninvasive imaging of the human brain and the use of this technique in animal studies using high magnetic fields is interesting.
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The neural basis of the blood-oxygen-level-dependent functional magnetic resonance imaging signal.
TL;DR: These findings, together with an analysis of the neural signals, indicate that the BOLD signal primarily measures the input and processing of neuronal information within a region and not the output signal transmitted to other brain regions.
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On the nature of the BOLD fMRI contrast mechanism
TL;DR: Current knowledge of the extracellularly measured signals of the neural processes that they represent and of the structural and functional neurovascular coupling, which links such processes with the hemodynamic changes that offer the surrogate signal that is used to map brain activity are discussed.
References
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Journal ArticleDOI
A theory of the effects of fibre size in medullated nerve
TL;DR: The interesting thing is that the nerve fibres do, in fact, exhibit the structural similarity demanded by the theory, and hence it is worth while to examine how far the variation in properties also accords with theoretical predictions.
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Conduction velocity and diameter of nerve fibers
TL;DR: The method employed is a favorable one from the standpoint of the conservation of fibers, as dissection is limited to freeing the nerves of adherent fascia, and it is not necessary to use small strands.
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Axon diameters in relation to the spike dimensions and the conduction velocity in mammalian a fibers
TL;DR: The problem of the relationship between the diameters of nerve fibers and the velocity at which the fibers conduct impulses cannot be considered solved until it is possible, within the range of a homogeneous group of fibers, to predict correctly the form of the action potential on the basis of the histological picture.
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The rôle played by the sizes of the constituent fibers of a nerve trunk in determining the form of its action potential wave
TL;DR: The nerve seems to be composed of fibers whose velocities of conduction form practically a continuous series from the fastest to the slowest, indicated by the growth of the area of the recorded wave as the stimulus is increased in size.