Factores de riesgo de muerte hospitalaria en pacientes con infarto agudo de miocardio durante la pandemia de la COVID-19
Jorge Solano-López,José Luis Zamorano,Ana Pardo Sanz,Ignacio J. Amat-Santos,Fernando Sarnago,Enrique Gutiérrez Ibañes,Juan Sanchis,Juan Ramón Rey Blas,Joan Antoni Gómez-Hospital,Sandra Santos Martínez,Nicolás Manuel Maneiro-Melón,Roberto Mateos Gaitán,Jessika González D’Gregorio,Luisa Salido,José Luis Mestre,Marcelo Sanmartín,Ángel Sánchez-Recalde +16 more
TLDR
In this article, an estudio of cohortes, prospectivo and multicentrico of todos the pacients consecutivos with IAM in tratamiento invasivo durante el brote de COVID-19 (15 de marzo a 15 de abril de 2020).Abstract:
Resumen Introduccion y objetivos A pesar de los avances en el tratamiento del infarto agudo de miocardio (IAM), este sigue presentando un pronostico desfavorable. Hay poca evidencia acerca de la evolucion de los pacientes con IAM y la enfermedad por coronavirus 2019 (COVID-19). El objetivo del estudio es describir la presentacion clinica, las complicaciones y los factores predictores de mortalidad hospitalaria en pacientes con IAM durante el brote de COVID-19 en Espana. Metodos Se realizo un estudio de cohortes, prospectivo y multicentrico de todos los pacientes consecutivos con IAM en tratamiento invasivo durante el brote de COVID-19 (15 de marzo a 15 de abril de 2020). Se compararon las caracteristicas clinicas de los pacientes positivos para COVID-19 con las de los negativos, y se evaluo el efecto de la COVID-19 en la mortalidad mediante emparejamiento por puntuacion de propension y regresion logistica. Resultados Se incluyo a 187 pacientes con IAM: 111 con elevacion del segmento ST y 76 sin elevacion. De ellos, 32 (17%) resultaron positivos para COVID-19. Las puntuaciones GRACE y Killip-Kimball y varios marcadores inflamatorios resultaron significativamente mayores en los pacientes con COVID-19. La mortalidad total y cardiovascular fueron significativamente mayores en los pacientes con COVID-19 (el 25 frente al 3,8%; p 140 (OR = 23,45; IC95%, 2,52-62,51; p = 0,005) y la COVID-19 (OR = 6,61; IC95%, 1,82-24,43; p = 0,02) resultaron factores independientes de mortalidad hospitalaria. Conclusiones Durante el brote epidemico, la puntuacion GRACE elevada y la COVID-19 fueron los factores independientes de mortalidad hospitalaria en los pacientes con IAM.read more
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Changes in Emergency Department Visits, Diagnostic Groups, and 28-Day Mortality Associated With the COVID-19 Pandemic: A Territory-Wide, Retrospective, Cohort Study.
Abraham K.C. Wai,Abraham K.C. Wai,Rafael Matos de Carvalho,Carlos K. H. Wong,Janet Yuen Ha Wong,Xi Xiong,Owen C. K. Chu,Man Sing Wong,Matthew Sik Hon Tsui,Timothy H. Rainer,Timothy H. Rainer +10 more
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