Journal ArticleDOI
Factors predicting outcomes of microwave ablation of small hepatocellular carcinoma
Anna Maria Ierardi,Francesca Giorlando,Filippo Piacentino,Federico Fontana,Raffaele Novario,Salvatore Alessio Angileri,Ejona Duka,Gianpaolo Carrafiello +7 more
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TLDR
The results encourage the role of MWA in the treatment of small HCC and to select cases in which MWA may be more effective and safer than RFA.Abstract:
The aim of our study was to evaluate factors influencing effectiveness of percutaneous microwave ablation (MWA) in patients with small hepatocellular carcinoma (HCC) ( 3 cm from the capsule) (n = 22) and peripheral (<3 cm from the capsule) (n = 43). Imaging follow-up was performed at 1, 3, 6, and 12 months after treatment, then annually. Mean follow-up period was 18 months (range 1–55). Location of the lesion, age, sex, and underlying disease of the patients was analyzed and related with efficacy. Technical success was obtained in all cases. Residual disease was registered in 21 lesions (32.3 %): 13 were peripheral and 8 were central. Twelve of them were retreated with percutaneous MWA. Local recurrence was recorded in 8 lesions (12.3 %): 5 were retreated with MWA. No significant difference in terms of effectiveness was observed in lesions located in a central position and those situated in the peripheral position. Age, sex, and underlying disease not influenced results. Only one major complication was observed. The rate of minor complications was 24.5 %. Mortality at 30 days was 0 %. Our results encourage the role of MWA in the treatment of small HCC. More numerous series and randomized studies are necessary to state the role of MWA and to select cases in which MWA may be more effective and safer than RFA.read more
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Immediate evaluation and guidance of liver cancer thermal ablation by three-dimensional ultrasound/contrast-enhanced ultrasound fusion imaging
TL;DR: 3D US-CEUS fusion imaging is a feasible and valuable technique for the immediate evaluation and guidance of supplementary ablation during the liver cancer thermal ablation procedure.
Journal ArticleDOI
Microwave ablation of liver malignancies: comparison of effects and early outcomes of percutaneous and intraoperative approaches with different liver conditions : New advances in interventional oncology: state of the art.
Francesco De Cobelli,Paolo Marra,Francesca Ratti,Alessandro Ambrosi,Michele Colombo,Anna Damascelli,Claudio Sallemi,Simone Gusmini,Marco Salvioni,Pietro Diana,Federica Cipriani,Massimo Venturini,Luca Aldrighetti,Alessandro Del Maschio +13 more
TL;DR: MWA with Thermosphere™ Technology produces predictable AZs on human liver in vivo, according to manufacturer-provided ex vivo predictions, and is effective and safe to treat liver malignancies in different operative and clinical settings.
Journal ArticleDOI
Flexible bronchoscopy-guided microwave ablation in peripheral porcine lung: a new minimally-invasive ablation
Yuan Haibin,Xiang-Yu Wang,Jiayuan Sun,Fangfang Xie,Xiaoxuan Zheng,Guang-Yu Tao,Lei Pan,Douglas K. Hogarth +7 more
TL;DR: The flexible bronchoscopy-guided water-cooled microwave ablation (MWA) catheter holds promise of MWA becoming a potential therapeutic tool for Peripheral Lung Cancers.
Journal ArticleDOI
A novel 3-dimensional electromagnetic guidance system increases intraoperative microwave antenna placement accuracy.
A. Sastry,Jacob H. Swet,Keith Murphy,Erin H. Baker,Dionisios Vrochides,John B. Martinie,Iain H. McKillop,David A. Iannitti +7 more
TL;DR: Empprint™ SX significantly improved accuracy and speed of antenna-placement independent of experience, and was particularly beneficial for novice users.
Journal ArticleDOI
Percutaneous US-guided MWA of small liver HCC: predictors of outcome and risk factors for complications from a single center experience
Pierpaolo Biondetti,Enrico Maria Fumarola,Anna Maria Ierardi,Andrea Coppola,Giovanna Gorga,Luca Maggi,Elena Valconi,Salvatore Alessio Angileri,Gianpaolo Carrafiello +8 more
TL;DR: Analysis of predictors of outcome and complications in patients with small hepatocellular carcinoma treated by percutaneous microwave ablation found significant factors related with complications and outcomes may be kept in mind when planning the best treatment for each patient.
References
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EASL-EORTC clinical practice guidelines : management of hepatocellular carcinoma
Peter R. Galle,Alejandro Forner,Josep M. Llovet,Vincenzo Mazzaferro,Fabio Piscaglia,Jean-Luc Raoul,Peter Schirmacher,Valérie Vilgrain +7 more
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Management of hepatocellular carcinoma: An update
Jordi Bruix,Morris Sherman +1 more
TL;DR: The American Association for the Study of Liver Diseases (AASLD) practice guidelines on the management of hepatocellular carcinoma (HCC) were updated in 2010 as discussed by the authors.
AASLD PRACTICE GUIDELINE Management of Hepatocellular Carcinoma: An Update
Jordi Bruix,Morris Sherman +1 more
TL;DR: Since the publication of the American Association for the Study of Liver Diseases (AASLD) practice guidelines on the management of hepatocellular carcinoma (HCC) in 2005, new information has emerged that requires that the guidelines be updated.
Journal Article
[New response evaluation criteria in solid tumours-revised RECIST guideline (version 1.1)].
Hirokazu Watanabe,Morihito Okada,Yasushi Kaji,Miyako Satouchi,Yozo Sato,Yuichiro Yamabe,Hiroaki Onaya,Masahiro Endo,Miyuki Sone,Yasuaki Arai +9 more
TL;DR: This paper is an overview of the new response evaluation criteria in solid tumours: revised RECIST guideline (version 1. 1), with a focus on updated contents.