Journal ArticleDOI
Food additive emulsifiers: a review of their role in foods, legislation and classifications, presence in food supply, dietary exposure, and safety assessment
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TLDR
Current research on the health effects of food additive emulsifiers are limited to in vitro and murine studies and small, acute studies in humans, and future research should focus on controlled human trials of longer duration.Abstract:
Food additive intakes have increased with the increase in "ultra-processed" food consumption. Food additive emulsifiers have received particular research attention in recent years due to preliminary evidence of adverse gastrointestinal and metabolic health effects. In this review, the use of emulsifiers as food additives is discussed, and the current estimations of exposure to, and safety of, emulsifiers are critically assessed. Food additive emulsifier research is complicated by heterogeneity in additives considered to be emulsifiers and labelling of them on foods globally. Major limitations exist in estimating food additive emulsifier exposure, relating predominantly to a lack of available food occurrence and concentration data. Development of brand-specific food additive emulsifier databases are crucial to accurately estimating emulsifier exposure. Current research on the health effects of food additive emulsifiers are limited to in vitro and murine studies and small, acute studies in humans, and future research should focus on controlled human trials of longer duration.read more
Citations
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Journal ArticleDOI
Direct impact of commonly used dietary emulsifiers on human gut microbiota.
TL;DR: In this article, the authors examined the extent to which a human microbiota, maintained ex vivo in the MiniBioReactor Array model, was impacted by 20 commonly used dietary emulsifiers.
Journal ArticleDOI
Dietary Emulsifiers Directly Impact Adherent-Invasive E. coli Gene Expression to Drive Chronic Intestinal Inflammation.
Emilie Viennois,Emilie Viennois,Alexis Bretin,Philip E. Dubé,Alexander C. Maue,Charlène J.G. Dauriat,Nicolas Barnich,Andrew T. Gewirtz,Benoit Chassaing,Benoit Chassaing +9 more
TL;DR: Dietary emulsifiers promote virulence and encroachment of pathobionts, providing a means by which these compounds may drive inflammation in hosts carrying such bacteria.
Journal ArticleDOI
Ultra-processed foods and human health: from epidemiological evidence to mechanistic insights.
Bernard Srour,Melissa C. Kordahi,Erica Bonazzi,Mélanie Deschasaux-Tanguy,Mathilde Touvier,Benoit Chassaing +5 more
TL;DR: In this article , an overview of the current data that highlight an association between ultra-processed food consumption and various chronic diseases, with a focus on epidemiological evidence and mechanistic insights involving the intestinal microbiota.
Journal ArticleDOI
Food Additive Emulsifiers and Their Impact on Gut Microbiome, Permeability, and Inflammation: Mechanistic Insights in Inflammatory Bowel Disease
Aaron S Bancil,Alicia M Sandall,Megan Rossi,Benoit Chassaing,Benoit Chassaing,James O. Lindsay,Kevin Whelan +6 more
TL;DR: A review of the current evidence for these mechanisms that may be of pathological relevance to IBD, evaluates recent dietary trials, acknowledges the challenges of dietary intervention studies, and gives an overview of ongoing and future clinical trials in this important area.
Journal ArticleDOI
Liquid and Solid Self-Emulsifying Drug Delivery Systems (SEDDs) as Carriers for the Oral Delivery of Azithromycin: Optimization, In Vitro Characterization and Stability Assessment.
Reem Abou Assi,Ibrahim M. Abdulbaqi,Toh Seok Ming,Chan Siok Yee,Habibah A. Wahab,Shaik Mohammed Asif,Yusrida Darwis +6 more
TL;DR: The developed SEDDs of AZM were proven to be cytocompatible and able to open up the cellular epithelial tight junctions (TJ) and stable at refrigerator storage conditions, suggesting the developed Seds may enhance the oral delivery of the drug.
References
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Journal ArticleDOI
Hydrocolloids at interfaces and the influence on the properties of dispersed systems
TL;DR: A review of literature evidence suggests that much of the reported emulsifying capability of polysaccharides is explicable in terms of complexation or contamination with a small fraction of surface-active protein this article.
Journal ArticleDOI
Dietary emulsifiers impact the mouse gut microbiota promoting colitis and metabolic syndrome
Benoit Chassaing,Omry Koren,Julia K. Goodrich,Angela C. Poole,Shanthi Srinivasan,Ruth E. Ley,Andrew T. Gewirtz +6 more
TL;DR: Results support the emerging concept that perturbed host–microbiota interactions resulting in low-grade inflammation can promote adiposity and its associated metabolic effects and suggest that the broad use of emulsifying agents might be contributing to an increased societal incidence of obesity/metabolic syndrome and other chronic inflammatory diseases.
Journal ArticleDOI
Ultra‐processed products are becoming dominant in the global food system
TL;DR: It is proposed here that the main driving force now shaping the global food system is transnational food manufacturing, retailing and fast food service corporations whose businesses are based on very profitable, heavily promoted ultra‐processed products, many in snack form.
Book
An Introduction to Food Colloids
TL;DR: The field of surface activity rheology emulsions foams proteins at liquid interfaces dispersions as discussed by the authors has been studied in the literature for several decades. But the field is still in its infancy.
Journal ArticleDOI
Making sense of the "clean label" trends: A review of consumer food choice behavior and discussion of industry implications.
Daniele Asioli,Daniele Asioli,Jessica Aschemann-Witzel,Vincenzina Caputo,Riccardo Vecchio,Azzurra Annunziata,Tormod Næs,Paula Varela +7 more
TL;DR: Results show that while 'health' is a major consumer motive, a broad diversity of drivers influence the clean label trend with particular relevance of intrinsic or extrinsic product characteristics and socio-cultural factors, however, 'free from' artificial additives/ingredients food products tend to differ from organic and natural products.