Frailty and Early Hospital Readmission After Kidney Transplantation
Mara McAdams-DeMarco,Andrew Law,Megan L. Salter,Eric K.H. Chow,Morgan E. Grams,Jeremy D. Walston,Dorry L. Segev,Dorry L. Segev +7 more
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TLDR
In this article, a measure of physiologic reserve, called frailty, was proposed as a predictor of early hospital readmission after kidney transplantation (EHR) in kidney transplant patients.About:
This article is published in American Journal of Transplantation.The article was published on 2013-08-01 and is currently open access. It has received 260 citations till now. The article focuses on the topics: Transplantation.read more
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Journal ArticleDOI
Frailty in Older Adults: A Nationally Representative Profile in the United States
Karen Bandeen-Roche,Christopher L. Seplaki,Jin Huang,Brian Buta,Rita R. Kalyani,Ravi Varadhan,Qian Li Xue,Jeremy D. Walston,Judith D. Kasper +8 more
TL;DR: The findings support the importance of frailty in late-life health etiology and potential value of frailt as a marker of risk for adverse health outcomes and as a means of identifying opportunities for intervention in clinical practice and public health policy.
Journal ArticleDOI
Frailty Predicts Waitlist Mortality in Liver Transplant Candidates
Jennifer C. Lai,Sandy Feng,Norah A. Terrault,Blanca Lizaola,Hilary Hayssen,Kenneth E. Covinsky +5 more
TL;DR: Frailty strongly predicts waitlist mortality, even after adjustment for liver disease severity, demonstrating the applicability and importance of the frailty construct in this population of liver transplant candidates.
Journal ArticleDOI
Frailty and cancer: Implications for oncology surgery, medical oncology, and radiation oncology.
Cecilia G. Ethun,Mehmet Asim Bilen,Ashesh B. Jani,Shishir K. Maithel,Kenneth Ogan,Viraj A. Master +5 more
TL;DR: The concept of frailty has become increasingly recognized as one of the most important issues in health care and health outcomes and is of particular importance in patients with cancer who are receiving treatment with surgery, chemotherapy, and radiotherapy as discussed by the authors.
Journal ArticleDOI
Frailty and Mortality in Kidney Transplant Recipients
Mara McAdams-DeMarco,Mara McAdams-DeMarco,Andrew Law,Elizabeth A. King,Elizabeth A. King,Babak J. Orandi,Babak J. Orandi,Megan L. Salter,Megan L. Salter,Natasha Gupta,Eric K.H. Chow,Nada Alachkar,Niraj M. Desai,Ravi Varadhan,Jeremy D. Walston,Dorry L. Segev,Dorry L. Segev +16 more
TL;DR: Regardless of age, frailty is a strong, independent risk factor for post‐KT mortality, even after carefully adjusting for many confounders using a novel, efficient statistical approach.
Journal ArticleDOI
Development and Initial Validation of the Risk Analysis Index for Measuring Frailty in Surgical Populations.
Daniel E. Hall,Shipra Arya,Kendra K. Schmid,Casey Blaser,Mark A. Carlson,Travis L. Bailey,Georgia Purviance,Tammy Bockman,Thomas G. Lynch,Jason M. Johanning +9 more
TL;DR: The RAi-C and RAI-A represent effective tools for measuring frailty in surgical populations with predictive ability on par with other frailty tools and Moderate correlation between the measures suggests convergent validity.
References
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Journal ArticleDOI
Sarcopenia and Mortality after Liver Transplantation
Michael J. Englesbe,Shaun P. Patel,Kevin He,Raymond J. Lynch,Douglas E. Schaubel,Calista M. Harbaugh,Sven A. Holcombe,Stewart C. Wang,Dorry L. Segev,Christopher J. Sonnenday +9 more
TL;DR: Central sarcopenia strongly correlates with mortality after liver transplantation and the impact of psoas area on survival exceeded that of all other covariates in these models.
Journal ArticleDOI
Inflammation and Frailty in Older Women
TL;DR: To evaluate relationships between white blood cell (WBC) count and interleukin‐6 (IL‐6) and prevalent frailty, a large number of animals were vaccinated for WBC and IL‐6 infection.
Journal ArticleDOI
Initial Manifestations of Frailty Criteria and the Development of Frailty Phenotype in the Women's Health and Aging Study II
TL;DR: It is suggested that weakness may serve as a warning sign of increasing vulnerability in early frailty development, and weight loss and exhaustion may help to identify women most at risk for rapid adverse progression.
Journal ArticleDOI
Insulin resistance and inflammation as precursors of frailty: The cardiovascular health study
Joshua I. Barzilay,Caroline S. Blaum,Tisha Moore,Qian Li Xue,Calvin H. Hirsch,Jeremy D. Walston,Linda P. Fried +6 more
TL;DR: Two physiologic components of MetS- IR-HOMA and inflammation-are associated with incident frailty and can be considered part of a larger process that leads to generalized decline.
Journal ArticleDOI
Frailty as a novel predictor of mortality and hospitalization in individuals of all ages undergoing hemodialysis.
Mara McAdams-DeMarco,Andrew Law,Andrew Law,Megan L. Salter,Megan L. Salter,Brian J. Boyarsky,Luis F. Gimenez,Bernard G. Jaar,Jeremy D. Walston,Dorry L. Segev,Dorry L. Segev +10 more
TL;DR: To quantify the prevalence of frailty in adults of all ages undergoing chronic hemodialysis, its relationship to comorbidity and disability, and its association with adverse outcomes of mortality and hospitalization.
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