Journal ArticleDOI
Frequency of idiopathic gastric stasis and intestinal transit disorders in essential dyspepsia.
TLDR
Almost 30% of patients with essential dyspepsia, predominantly women, in whom statistical analysis failed to reveal any specific pattern of symptoms, had significantly delayed gastric emptying suggesting idiopathic gastric stasis.Abstract:
Gastric emptying, mouth-to-cecum transit (MCT), and whole-gut transit of a solid-liquid meal was measured in 30 control subjects and in 43 patients with essential dyspepsia, in whom organic digestive diseases and secondary disorders of gastric emptying had been excluded. The rate of gastric emptying was determined by an anterior gamma camera technique, MCT by the hydrogen breath test, and whole-gut transit by the first appearance of stool markers. Approximately 30% of patients with essential dyspepsia, predominantly women, in whom statistical analysis failed to reveal any specific pattern of symptoms, had significantly delayed gastric emptying suggesting idiopathic gastric stasis. Concerning MCT and whole-gut transit, significant differences between the control and study group could not be detected.read more
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Journal ArticleDOI
Pathophysiology and treatment of functional dyspepsia.
Journal ArticleDOI
Ghrelin stimulates gastric emptying and hunger in normal-weight humans.
Fredrik Levin,T. Edholm,Peter T. Schmidt,P Grybäck,Hans Jacobsson,Marie Degerblad,Charlotte Höybye,Jens J. Holst,Jens F. Rehfeld,Per M. Hellström,Erik Näslund +10 more
TL;DR: It is demonstrated that ghrelin increases the gastric emptying rate in normal humans and the effect does not seem to be mediated via GH or motilin but may be mediated by the vagal nerve or directly on gh Relin receptors in the stomach.
Journal ArticleDOI
Abnormal intragastric distribution of food during gastric emptying in functional dyspepsia patients.
TL;DR: It is concluded that this subgroup of functional dyspepsia patients show abnormal intragastric distribution of food, independent of gastric emptying rate.
Journal ArticleDOI
Impaired accommodation of proximal stomach to a meal in functional dyspepsia
TL;DR: Patients with functional dyspepsia have impaired accommodation of the proximal stomach to a meal, temporarily related to symptom induction, and they suffered more symptoms in response to the meal.
Journal ArticleDOI
The patterns of small bowel motility: physiology and implications in organic disease and functional disorders.
TL;DR: Although specific disease diagnosis cannot be made by motility studies of the small bowel, the functional integrity is revealed and the normal occurrence of the essential patterns and periods of motility and the absence of distinctly abnormal patterns evidence preserved function, whereas the opposite indicates clinically significant dysmotility.