J
Jan Tack
Researcher at Katholieke Universiteit Leuven
Publications - 1277
Citations - 58536
Jan Tack is an academic researcher from Katholieke Universiteit Leuven. The author has contributed to research in topics: Gastric emptying & Medicine. The author has an hindex of 110, co-authored 1185 publications receiving 49774 citations. Previous affiliations of Jan Tack include Boston Children's Hospital & University of Amsterdam.
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Journal ArticleDOI
Functional gastroduodenal disorders
Jan Tack,Nicholas J. Talley,Michael Camilleri,Gerald Holtmann,Pinjin Hu,Juan R. Malagelada,Vincenzo Stanghellini +6 more
TL;DR: A consensus-based approach was applied, supplemented by input from international experts who reviewed the report, and a dyspepsia subgroup classification is proposed for research purposes, based on the predominant (most bothersome) symptom.
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The Serotonin Signaling System: From Basic Understanding To Drug Development for Functional GI Disorders
Michael D. Gershon,Jan Tack +1 more
TL;DR: Serotonin is an important gastrointestinal signaling molecule as mentioned in this paper, which is used by enterochromaffin (EC) cells to activate intrinsic and extrinsic primary afferent neurons to initiate peristaltic and secretory reflexes and transmit information to the central nervous system.
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Kyoto global consensus report on Helicobacter pylori gastritis
Kentaro Sugano,Jan Tack,Ernst J. Kuipers,David Y. Graham,Emad M. El-Omar,Soichiro Miura,Ken Haruma,Masahiro Asaka,Naomi Uemura,Peter Malfertheiner +9 more
TL;DR: A global consensus for gastritis was developed for the first time, which will be the basis for an international classification system and for further research on the subject.
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Role of impaired gastric accommodation to a meal in functional dyspepsia
TL;DR: Impaired relaxation of the proximal stomach to a meal is present in a high proportion of patients with functional dyspepsia and is associated with symptoms of early satiety, and restoring gastric accommodation with a fundus-relaxing drug improves early satieties.
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Modern diagnosis of GERD: the Lyon Consensus
C. Prakash Gyawali,Peter J. Kahrilas,Edoardo Savarino,Frank Zerbib,François Mion,François Mion,André J.P.M. Smout,Michael F. Vaezi,Daniel Sifrim,Mark A. Fox,Marcelo F. Vela,Radu Tutuian,Jan Tack,Albert J. Bredenoord,John E. Pandolfino,Sabine Roman,Sabine Roman +16 more
TL;DR: Future GERD management strategies should focus on defining individual patient phenotypes based on the level of refluxate exposure, mechanism of refux, efficacy of clearance, underlying anatomy of the oesophagogastric junction and psychometrics defining symptomatic presentations.