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Genes to cells
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The article was published on 1996-01-01 and is currently open access. It has received 510 citations till now. The article focuses on the topics: Gene.read more
Citations
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Journal ArticleDOI
Autophagy: Renovation of Cells and Tissues
Noboru Mizushima,Masaaki Komatsu +1 more
TL;DR: It is explored how recent mouse models in combination with advances in human genetics are providing key insights into how the impairment or activation of autophagy contributes to pathogenesis of diverse diseases, from neurodegenerative diseases such as Parkinson disease to inflammatory disorders such as Crohn disease.
Journal ArticleDOI
Epigenetic Reprogramming in Mammalian Development
Wolf Reik,Wendy Dean,Jörn Walter +2 more
TL;DR: What is known about reprogramming in mammals and how it might relate to developmental potency and imprinting are discussed, including whether or not methylation is involved in the control of gene expression during normal development.
Journal ArticleDOI
Molecular Bases for Circadian Clocks
TL;DR: It used to be that research in chronobiology moved biochemical functions [transcriptional activators], the along at a gentlemanly pace, but by mid 1997 the word in determining what the authors perceive as time was PASWCCLK.
Journal ArticleDOI
lincRNAs: genomics, evolution, and mechanisms.
Igor Ulitsky,David P. Bartel +1 more
TL;DR: This Review outlines the emerging understanding of lincRNAs in vertebrate animals, with emphases on how they are being identified and current conclusions and questions regarding their genomics, evolution and mechanisms of action.
Journal ArticleDOI
DNA replication in eukaryotic cells
Stephen P. Bell,Anindya Dutta +1 more
TL;DR: This review describes the current understanding of the events of initiation of eukaryotic replication factors and how they are coordinated with cell cycle progression and emphasizes recent progress in determining the function of the different replication factors once they have been assembled at the origin.
References
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Journal ArticleDOI
Autophagy: Renovation of Cells and Tissues
Noboru Mizushima,Masaaki Komatsu +1 more
TL;DR: It is explored how recent mouse models in combination with advances in human genetics are providing key insights into how the impairment or activation of autophagy contributes to pathogenesis of diverse diseases, from neurodegenerative diseases such as Parkinson disease to inflammatory disorders such as Crohn disease.
Journal ArticleDOI
Epigenetic Reprogramming in Mammalian Development
Wolf Reik,Wendy Dean,Jörn Walter +2 more
TL;DR: What is known about reprogramming in mammals and how it might relate to developmental potency and imprinting are discussed, including whether or not methylation is involved in the control of gene expression during normal development.
Journal ArticleDOI
Molecular Bases for Circadian Clocks
TL;DR: It used to be that research in chronobiology moved biochemical functions [transcriptional activators], the along at a gentlemanly pace, but by mid 1997 the word in determining what the authors perceive as time was PASWCCLK.
Journal ArticleDOI
lincRNAs: genomics, evolution, and mechanisms.
Igor Ulitsky,David P. Bartel +1 more
TL;DR: This Review outlines the emerging understanding of lincRNAs in vertebrate animals, with emphases on how they are being identified and current conclusions and questions regarding their genomics, evolution and mechanisms of action.
Journal ArticleDOI
DNA replication in eukaryotic cells
Stephen P. Bell,Anindya Dutta +1 more
TL;DR: This review describes the current understanding of the events of initiation of eukaryotic replication factors and how they are coordinated with cell cycle progression and emphasizes recent progress in determining the function of the different replication factors once they have been assembled at the origin.