Journal ArticleDOI
Globin mRNA sequences: analysis of base pairing and evolutionary implications.
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This article is published in Cold Spring Harbor Symposia on Quantitative Biology.The article was published on 1978-01-01. It has received 355 citations till now. The article focuses on the topics: Mutation (genetic algorithm) & Base pair.read more
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Mfold web server for nucleic acid folding and hybridization prediction
TL;DR: The objective of this web server is to provide easy access to RNA and DNA folding and hybridization software to the scientific community at large by making use of universally available web GUIs (Graphical User Interfaces).
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Slipped-strand mispairing: a major mechanism for DNA sequence evolution.
G Levinson,George A. Gutman +1 more
TL;DR: Evidence is presented that single-base repeats (the shortest possible motifs) are represented by longer runs in mammalian introns than would be expected on a random basis, supporting the idea that SSM may be a ubiquitous force in the evolution of the eukaryotic genome.
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On finding all suboptimal foldings of an RNA molecule
TL;DR: The mathematical problem of determining how well defined a minimum energy folding is can now be solved and all predicted base pairs that can participate in suboptimal structures may be displayed and analyzed graphically.
Journal ArticleDOI
Improved free-energy parameters for predictions of RNA duplex stability
Susan M. Freier,Ryszard Kierzek,John A. Jaeger,Naoki Sugimoto,Marvin H. Caruthers,Thomas Neilson,Douglas H. Turner +6 more
TL;DR: These parameters predict melting temperatures of most oligonucleotide duplexes within 5 degrees C, about as good as can be expected from the nearest-neighbor model.
Journal ArticleDOI
The equilibrium partition function and base pair binding probabilities for RNA secondary structure
TL;DR: A novel application of dynamic programming to the folding problem for RNA enables one to calculate the full equilibrium partition function for secondary structure and the probabilities of various substructures by a recursive scheme of polynomial order N3 in the sequence length N.